Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Glomerulonephritis membranous
ADR ID BADD_A01850
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.007      Glomerulonephritis membranous
Description A type of glomerulonephritis that is characterized by the accumulation of immune deposits (COMPLEMENT MEMBRANE ATTACK COMPLEX) on the outer aspect of the GLOMERULAR BASEMENT MEMBRANE. It progresses from subepithelial dense deposits, to basement membrane reaction and eventual thickening of the basement membrane. | An experimental rat model of human membranous nephropathy characterized by complement activation and formation of subepithelial immune deposits in the glomerular capillary wall. [MeSH]
MedDRA Code 10018372
MeSH ID D015433
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Glomerulonephritis membranous | Glomerulonephritis membranous chronic | Membranous nephropathy | Nephritis and nephropathy, not specified as acute or chronic, with lesion of membranous glomneph | Glomerulonephritis, Membranous | Glomerulonephritides, Membranous | Membranous Glomerulonephritides | Membranous Glomerulonephritis | Nephropathy, Membranous | Membranous Glomerulopathy | Glomerulopathy, Membranous | Membranous Nephropathy | Extramembranous Glomerulopathy | Glomerulopathy, Extramembranous | Membranous Glomerulonephropathy | Glomerulonephropathy, Membranous | Idiopathic Membranous Glomerulonephritis | Glomerulonephritides, Idiopathic Membranous | Glomerulonephritis, Idiopathic Membranous | Idiopathic Membranous Glomerulonephritides | Membranous Glomerulonephritides, Idiopathic | Membranous Glomerulonephritis, Idiopathic | Idiopathic Membranous Nephropathy | Membranous Nephropathy, Idiopathic | Nephropathy, Idiopathic Membranous | Heymann Nephritis | Nephritis, Heymann
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00071Alglucosidase alfa--
BADD_D00191Auranofin--
BADD_D00306Budesonide0.000093%
BADD_D00504Clopidogrel0.000021%
BADD_D00551Cyclosporine0.000221%
BADD_D00556Cysteamine--
BADD_D00979Furosemide0.000014%
BADD_D01081Hydralazine0.000170%
BADD_D01119Ibrutinib0.000112%
BADD_D01120Ibuprofen0.000013%
BADD_D01252Leflunomide0.000428%
BADD_D01507Mycophenolate mofetil--
BADD_D01511Nabumetone0.000260%
BADD_D01709Penicillamine--
BADD_D01831Prednisolone0.000052%
BADD_D01835Pregabalin0.000052%
BADD_D01933Ribavirin0.003956%
BADD_D01940Rilpivirine--
BADD_D01941Rilpivirine hydrochloride--
BADD_D01954Rivaroxaban0.000063%
BADD_D02100Sunitinib0.000168%
BADD_D02105Tacrolimus0.001337%
BADD_D02264Trastuzumab--
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