Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Goitre
ADR ID BADD_A01867
ADR Hierarchy
05      Endocrine disorders
05.02      Thyroid gland disorders
05.02.01      Thyroid disorders NEC
05.02.01.001      Goitre
14      Metabolism and nutrition disorders
14.11      Metabolism disorders NEC
14.11.01      Metabolic disorders NEC
14.11.01.008      Goitre
Description Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC). [MeSH]
MedDRA Code 10018498
MeSH ID D006042; D006043
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Dyshormonogenic goiter | Dyshormonogenic goitre | Enlarged thyroid | Goiter | Goiter diffuse | Goiter nodular | Goiter, specified as simple | Goiter, unspecified | Goitre | Goitre nontoxic | Goitre, specified as simple | Goitre, unspecified | Non-toxic multinodular goitre | Non-toxic nodular goitre | Non-toxic uninodular goitre | Nontoxic goiter | Nontoxic goitre | Nontoxic multinodular goiter | Nontoxic multinodular goitre | Nontoxic nodular goiter | Nontoxic nodular goitre | Nontoxic nodular goitre, unspecified | Nontoxic uninodular goiter | Nontoxic uninodular goitre | Simple and unspecified goiter | Simple and unspecified goitre | Simple goitre | Thyroid enlarged | Unspecified nontoxic nodular goiter | Unspecified nontoxic nodular goitre | Adenomatous goitre | Thyroid hyperplasia | Adenomatous goiter | Goitre diffuse | Goitre nodular | Euthyroid goiter | Euthyroid goitre | Iodine deficiency goiter | Iodine deficiency goitre | Parenchymatous goitre | Parenchymatous goiter | Thyromegaly | Asymmetric thyroid | Endemic goiter | Endemic goitre | Transient thyroid enlargement | Plunging goitre | Plunging goiter | Simple goiter | Multinodular goitre | Multinodular goiter | Heterogenous nodular goitre | Heterogenous nodular goiter | Secondary substernal goiter | Substernal thyroid | Secondary substernal goitre | Thyroid gland swelling | Struma | Thyroid hypertrophy | Struma nodosa | Compressive goiter | Compressive goitre | Goiters
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00821Estradiol--
BADD_D00858Everolimus0.000229%
BADD_D00898Finasteride0.000135%
BADD_D00932Fluoxetine--
BADD_D00950Fluvoxamine--
BADD_D00951Fluvoxamine maleate--
BADD_D00981Gabapentin--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01095Hydrogen iodide--
BADD_D01162Insulin detemir--
BADD_D01167Interferon alfa-2b--
BADD_D01243Lamotrigine--
BADD_D01245Lansoprazole--
BADD_D01260Leuprolide acetate--
BADD_D01261Leuprolide monoacetate--
BADD_D01281Levonorgestrel0.001182%
BADD_D01285Levothyroxine0.000032%
BADD_D01302Lithium--
BADD_D01303Lithium carbonate0.001874%
BADD_D01304Lithium cation0.000960%
BADD_D01305Lithium hydroxide--
BADD_D01397Mesalamine0.000183%
BADD_D01401Metformin0.000008%
BADD_D01414Methimazole0.000202%
BADD_D01418Methotrexate0.000171%
BADD_D01433Methylprednisolone0.000032%
BADD_D01470Minocycline0.000437%
BADD_D01476Mirtazapine--
BADD_D01558Nexium--
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