Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Goodpasture's syndrome
ADR ID BADD_A01870
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.04      Autoimmune disorders NEC
10.04.04.006      Goodpasture's syndrome
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.009      Goodpasture's syndrome
22      Respiratory, thoracic and mediastinal disorders
22.01      Lower respiratory tract disorders (excl obstruction and infection)
22.01.01      Lower respiratory tract inflammatory and immunologic conditions
22.01.01.010      Goodpasture's syndrome
Description An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis. [MeSH]
MedDRA Code 10018620
MeSH ID D019867
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Goodpasture's syndrome | Syndrome Good pasture | Syndrome Good postures | Syndrome Goodpasture's | Anti-Glomerular Basement Membrane Disease | Anti Glomerular Basement Membrane Disease | Anti-GBM Disease | Anti GBM Disease | Lung Purpura with Nephritis | Goodpasture's Syndrome | Goodpastures Syndrome | Syndrome, Goodpasture's | Goodpasture Syndrome | Syndrome, Goodpasture
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00064Alemtuzumab--
BADD_D01709Penicillamine--
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