Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Haemochromatosis
ADR ID BADD_A01917
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.10      Hepatic metabolic disorders
09.01.10.005      Haemochromatosis
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.08      Transfusion related complications
12.02.08.002      Haemochromatosis
14      Metabolism and nutrition disorders
14.13      Iron and trace metal metabolism disorders
14.13.03      Iron excess
14.13.03.001      Haemochromatosis
Description A disorder of iron metabolism characterized by a triad of HEMOSIDEROSIS; LIVER CIRRHOSIS; and DIABETES MELLITUS. It is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed) [MeSH]
MedDRA Code 10018872
MeSH ID D006432
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bronzed diabetes | Haemochromatosis | Hemochromatosis | Secondary haemochromatosis | Secondary hemochromatosis | Bronzed Cirrhosis | Bronzed Cirrhoses | Cirrhoses, Bronzed | Cirrhosis, Bronzed | Diabetes, Bronze | Haemochromatoses | Von Recklenhausen-Applebaum Disease | Disease, Von Recklenhausen-Applebaum | Diseases, Von Recklenhausen-Applebaum | Recklenhausen-Applebaum Disease, Von | Recklenhausen-Applebaum Diseases, Von | Von Recklenhausen Applebaum Disease | Von Recklenhausen-Applebaum Diseases | Bronze Diabetes | Iron Storage Disorder | Disorder, Iron Storage | Disorders, Iron Storage | Iron Storage Disorders | Storage Disorder, Iron | Storage Disorders, Iron | Pigmentary Cirrhosis | Cirrhoses, Pigmentary | Cirrhosis, Pigmentary | Pigmentary Cirrhoses | Troisier-Hanot-Chauffard Syndrome | Syndrome, Troisier-Hanot-Chauffard | Syndromes, Troisier-Hanot-Chauffard | Troisier Hanot Chauffard Syndrome | Troisier-Hanot-Chauffard Syndromes | Hemochromatoses | Hemochromatose | Familial Hemochromatosis | Familial Hemochromatoses | Hemochromatoses, Familial | Hemochromatosis, Familial | Primary Hemochromatosis | Genetic Hemochromatosis | Genetic Hemochromatoses | Hemochromatoses, Genetic | Hemochromatosis, Genetic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00511Clozapine0.001834%
BADD_D00594Deferasirox0.013878%
BADD_D00596Deferoxamine0.002726%
BADD_D01253Lenalidomide--
BADD_D01418Methotrexate0.000387%
BADD_D01954Rivaroxaban0.000171%
BADD_D01971Rosuvastatin0.000017%
BADD_D01978Ruxolitinib0.000137%
BADD_D02184Tetraferric tricitrate decahydrate0.001239%
BADD_D02346Venlafaxine--
BADD_D02436Atorvastatin0.000005%
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