Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Henoch-Schonlein purpura
ADR ID BADD_A01989
ADR Hierarchy
01      Blood and lymphatic system disorders
01.01      Coagulopathies and bleeding diatheses (excl thrombocytopenic)
01.01.04      Purpuras (excl thrombocytopenic)
01.01.04.001      Henoch-Schonlein purpura
10      Immune system disorders
10.02      Immune disorders NEC
10.02.02      Vasculitides
10.02.02.004      Henoch-Schonlein purpura
23      Skin and subcutaneous tissue disorders
23.06      Skin vascular abnormalities
23.06.01      Purpura and related conditions
23.06.01.002      Henoch-Schonlein purpura
24      Vascular disorders
24.07      Vascular haemorrhagic disorders
24.07.06      Bruising, ecchymosis and purpura
24.07.06.003      Henoch-Schonlein purpura
Description A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections. [MeSH]
MedDRA Code 10019617
MeSH ID D011695
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Allergic purpura | Allergic vascular purpura | Anaphylactic vascular purpura | Anaphylactoid purpura | Anaphylactoid vascular purpura | Henoch Shonlein purpura | Henoch-Schonlein | Henoch-Schonlein purpura | Purpura allergic | Purpura anaphylactoid | Purpura vascular allergic | Schoenlein-Henoch purpura | Vasculitis Henoch-Schonlein like | Rheumatic purpura | IgA vasculitis | Immunoglobulin A-associated vasculitis | Purpura, Schoenlein-Henoch | Purpura, Schoenlein Henoch | Anaphylactoid Purpura | Purpura, Anaphylactoid | Henoch Purpura | Purpura, Henoch | Purpura, Schonlein-Henoch | Purpura, Schonlein Henoch | Purpuras, Schonlein-Henoch | Schonlein-Henoch Purpura | Schonlein-Henoch Purpuras | Schoenlein-Henoch Purpura | Schoenlein Henoch Purpura | Henoch-Schonlein Purpura | Henoch-Schonlein Purpuras | Purpura, Henoch-Schonlein | Purpuras, Henoch-Schonlein | Henoch Schonlein Purpura | Henoch Schonlein Purpuras | Purpura, Henoch Schonlein | Purpuras, Henoch Schonlein | Schonlein Purpura, Henoch | Schonlein Purpuras, Henoch | Allergic Purpura | Purpura, Allergic | Henoch-Schoenlein Purpura | Henoch Schoenlein Purpura | Purpura, Henoch-Schoenlein | Vasculitis, Hemorrhagic | Hemorrhagic Vasculitis | Rheumatoid Purpura | Purpura, Rheumatoid | Purpura Hemorrhagica | Hemorrhagica, Purpura | Purpura, Nonthrombocytopenic | Nonthrombocytopenic Purpura | Purpura, Nonthrombopenic | Nonthrombopenic Purpura | Nonthrombopenic Purpuras | Purpuras, Nonthrombopenic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00129Amoxicillin0.000036%
BADD_D00142Anastrozole0.000397%
BADD_D00151Apixaban0.000130%
BADD_D00195Azathioprine0.000313%
BADD_D00306Budesonide0.000251%
BADD_D00347Candesartan cilexetil0.001262%
BADD_D00359Carbidopa--
BADD_D00405Ceftriaxone0.006685%
BADD_D00410Celecoxib0.000099%
BADD_D00480Clarithromycin0.000335%
BADD_D00483Clindamycin--
BADD_D00504Clopidogrel0.000043%
BADD_D00594Deferasirox--
BADD_D00595Deferiprone--
BADD_D00605Demeclocycline--
BADD_D00606Demeclocycline hydrochloride--
BADD_D00653Diclofenac0.000051%
BADD_D00725Doxycycline--
BADD_D00726Doxycycline calcium--
BADD_D00727Doxycycline hyclate--
BADD_D00728Doxycycline monohydrate--
BADD_D00800Erlotinib0.000168%
BADD_D00839Ethacrynate sodium--
BADD_D00840Ethacrynic acid--
BADD_D00871Felbamate--
BADD_D00932Fluoxetine0.000039%
BADD_D00950Fluvoxamine--
BADD_D00951Fluvoxamine maleate--
BADD_D00974Fragmin--
BADD_D01083Hydrochlorothiazide--
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