Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Henoch-Schonlein purpura
ADR ID BADD_A01989
ADR Hierarchy
01      Blood and lymphatic system disorders
01.01      Coagulopathies and bleeding diatheses (excl thrombocytopenic)
01.01.04      Purpuras (excl thrombocytopenic)
01.01.04.001      Henoch-Schonlein purpura
10      Immune system disorders
10.02      Immune disorders NEC
10.02.02      Vasculitides
10.02.02.004      Henoch-Schonlein purpura
23      Skin and subcutaneous tissue disorders
23.06      Skin vascular abnormalities
23.06.01      Purpura and related conditions
23.06.01.002      Henoch-Schonlein purpura
24      Vascular disorders
24.07      Vascular haemorrhagic disorders
24.07.06      Bruising, ecchymosis and purpura
24.07.06.003      Henoch-Schonlein purpura
Description A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections. [MeSH]
MedDRA Code 10019617
MeSH ID D011695
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Allergic purpura | Allergic vascular purpura | Anaphylactic vascular purpura | Anaphylactoid purpura | Anaphylactoid vascular purpura | Henoch Shonlein purpura | Henoch-Schonlein | Henoch-Schonlein purpura | Purpura allergic | Purpura anaphylactoid | Purpura vascular allergic | Schoenlein-Henoch purpura | Vasculitis Henoch-Schonlein like | Rheumatic purpura | IgA vasculitis | Immunoglobulin A-associated vasculitis | Purpura, Schoenlein-Henoch | Purpura, Schoenlein Henoch | Anaphylactoid Purpura | Purpura, Anaphylactoid | Henoch Purpura | Purpura, Henoch | Purpura, Schonlein-Henoch | Purpura, Schonlein Henoch | Purpuras, Schonlein-Henoch | Schonlein-Henoch Purpura | Schonlein-Henoch Purpuras | Schoenlein-Henoch Purpura | Schoenlein Henoch Purpura | Henoch-Schonlein Purpura | Henoch-Schonlein Purpuras | Purpura, Henoch-Schonlein | Purpuras, Henoch-Schonlein | Henoch Schonlein Purpura | Henoch Schonlein Purpuras | Purpura, Henoch Schonlein | Purpuras, Henoch Schonlein | Schonlein Purpura, Henoch | Schonlein Purpuras, Henoch | Allergic Purpura | Purpura, Allergic | Henoch-Schoenlein Purpura | Henoch Schoenlein Purpura | Purpura, Henoch-Schoenlein | Vasculitis, Hemorrhagic | Hemorrhagic Vasculitis | Rheumatoid Purpura | Purpura, Rheumatoid | Purpura Hemorrhagica | Hemorrhagica, Purpura | Purpura, Nonthrombocytopenic | Nonthrombocytopenic Purpura | Purpura, Nonthrombopenic | Nonthrombopenic Purpura | Nonthrombopenic Purpuras | Purpuras, Nonthrombopenic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02179Tetracycline--
BADD_D02180Tetracycline anion--
BADD_D02181Tetracycline hydrochloride--
BADD_D02222Tinzaparin sodium--
BADD_D02329Valproic acid0.000200%
BADD_D02367Voltaren--
BADD_D02373Warfarin0.000028%
BADD_D02473Sodium chloride0.000362%
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