Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hepatic cirrhosis
ADR ID BADD_A01995
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.04      Hepatic fibrosis and cirrhosis
09.01.04.001      Hepatic cirrhosis
Description Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. [MeSH]
MedDRA Code 10019641
MeSH ID D008103
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic liver disease and cirrhosis | Cirrhosis liver | Cirrhosis liver postnecrotic | Cirrhosis of liver | Cirrhosis of liver without mention of alcohol | Hepatic cirrhosis | Hepatic cirrhosis NOS | Hepatic cirrhosis post necrotic | Liver cirrhosis | Cirrhosis liver post necrotic | Decompensated cirrhosis | Compensated cirrhosis | Micronodular cirrhosis | Incomplete septal cirrhosis | Liver Cirrhosis | Cirrhosis, Liver | Cirrhoses, Liver | Liver Cirrhoses | Hepatic Cirrhosis | Cirrhoses, Hepatic | Cirrhosis, Hepatic | Hepatic Cirrhoses | Fibrosis, Liver | Fibroses, Liver | Liver Fibroses | Liver Fibrosis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01220Ivacaftor-
BADD_D01238Lacosamide0.001463%
BADD_D01240Lactulose0.000403%
BADD_D01242Lamivudine0.001012%
BADD_D01252Leflunomide0.000428%
BADD_D01257Letrozole0.000263%
BADD_D01260Leuprolide acetate0.002151%
BADD_D01285Levothyroxine0.000015%
BADD_D01292Linagliptin0.000243%
BADD_D01295Linezolid0.002470%
BADD_D01318Lorazepam0.000083%
BADD_D01322Losartan0.000020%
BADD_D01336Macitentan0.001769%
BADD_D01352Maraviroc0.000282%
BADD_D01401Metformin0.000041%
BADD_D01405Methadone0.000796%
BADD_D01418Methotrexate0.001706%
BADD_D01419Methotrexate sodium--
BADD_D01445Metoprolol0.000013%
BADD_D01449Metronidazole0.000053%
BADD_D01476Mirtazapine--
BADD_D01498Morphine--
BADD_D01533Naproxen--
BADD_D01567Nilotinib0.000616%
BADD_D01572Nitisinone0.030187%
BADD_D01592Obeticholic acid0.019390%
BADD_D01599Olanzapine0.000947%
BADD_D01601Olaparib0.000168%
BADD_D01602Olmesartan0.000105%
BADD_D01633Oxaliplatin0.000660%
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ADReCS-Target
ADR Term Drug Name Target