Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hepatic necrosis
ADR ID BADD_A02009
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.07      Hepatocellular damage and hepatitis NEC
09.01.07.002      Hepatic necrosis
Description A disorder characterized by a necrotic process occurring in the hepatic parenchyma. [CTCAE]
MedDRA Code 10019692
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute and subacute necrosis of liver | Hepatic lobule necrosis | Hepatic necrosis | Hepatic necrosis extensive | Hepatitis necrotizing | Liver necrosis | Necrosis hepatocellular | Necrosis liver | Necrosis liver focal | Subacute hepatic necrosis | Hepatitis necrotising
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01864Propofol0.000179%
BADD_D01909Ramipril--
BADD_D01933Ribavirin0.003956%
BADD_D01954Rivaroxaban0.000158%
BADD_D02015Sevoflurane--
BADD_D02022Silvadene--
BADD_D02026Simvastatin0.000015%
BADD_D02028Sirolimus--
BADD_D02058Sorafenib0.000224%
BADD_D02062Sparfloxacin--
BADD_D02066Spironolactone0.000037%
BADD_D02088Sulfacetamide--
BADD_D02090Sulfadiazine--
BADD_D02091Sulfamethoxazole--
BADD_D02093Sulfasalazine0.000303%
BADD_D02105Tacrolimus0.000297%
BADD_D02111Tamoxifen--
BADD_D02112Tamoxifen citrate--
BADD_D02146Telithromycin--
BADD_D02154Tenofovir0.001939%
BADD_D02199Thioguanine--
BADD_D02215Ticlopidine--
BADD_D02216Ticlopidine hydrochloride--
BADD_D02230Tizanidine--
BADD_D02290Trimethoprim--
BADD_D02302Tromethamine--
BADD_D02329Valproic acid0.000200%
BADD_D02367Voltaren--
BADD_D02394Zolpidem0.000025%
BADD_D02436Atorvastatin0.000015%
The 5th Page    First    Pre   5 6    Next   Last    Total 6 Pages
ADReCS-Target
ADR Term Drug Name Target