Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hepatic steatosis
ADR ID BADD_A02014
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.07      Hepatocellular damage and hepatitis NEC
09.01.07.003      Hepatic steatosis
14      Metabolism and nutrition disorders
14.08      Lipid metabolism disorders
14.08.04      Lipid metabolism and deposit disorders NEC
14.08.04.005      Hepatic steatosis
Description Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS. | Inflammation of the liver related to lipid accumulation in fatty liver. [MeSH]
MedDRA Code 10019708
MeSH ID D005234
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Degeneration fatty liver | Fatty liver | Fatty liver infiltration | Fatty liver metamorphosis | Hepatic macrosteatosis | Hepatic microsteatosis | Hepatic steatosis | Infiltration fatty liver | Liver fatty | Liver fatty change | Liver fatty degeneration | Liver fatty deposit | Liver fatty deposition | Liver fatty infiltration | Liver fatty metamorphosis | Liver fatty phanerosis | Metamorphosis fatty liver | Microvesicular fat disease of liver | Phanerosis fatty liver | Steatosis hepatic | Focal hepatic steatosis | Fatty Liver | Liver, Fatty | Steatohepatitis | Steatohepatitides | Steatosis of Liver | Visceral Steatosis | Steatoses, Visceral | Steatosis, Visceral | Visceral Steatoses | Liver Steatosis | Liver Steatoses | Steatoses, Liver | Steatosis, Liver
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00661Didanosine--
BADD_D00680Dimethyl fumarate0.005481%
BADD_D00723Doxorubicin0.000112%
BADD_D00725Doxycycline0.000022%
BADD_D00734Duloxetine0.000277%
BADD_D00735Duloxetine hydrochloride--
BADD_D00736Dutasteride0.000228%
BADD_D00749Efavirenz--
BADD_D00765Empagliflozin0.000555%
BADD_D00766Emtricitabine--
BADD_D00771Enfuvirtide--
BADD_D00774Entecavir0.003269%
BADD_D00798Eribulin0.000437%
BADD_D00809Escitalopram0.000019%
BADD_D00856Etoricoxib--
BADD_D00857Etravirine--
BADD_D00858Everolimus0.000688%
BADD_D00870Febuxostat0.000826%
BADD_D00873Fenofibrate0.000039%
BADD_D00898Finasteride0.000422%
BADD_D00931Fluorouracil0.000460%
BADD_D00932Fluoxetine0.000069%
BADD_D00948Fluvastatin--
BADD_D00949Fluvastatin sodium--
BADD_D00981Gabapentin0.000060%
BADD_D01009Gemcitabine0.000224%
BADD_D01012Gemfibrozil0.000107%
BADD_D01103Hydroxychloroquine0.002789%
BADD_D01136Imatinib0.000448%
BADD_D01204Isoniazid0.006115%
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ADReCS-Target
ADR Term Drug Name Target