Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hepatitis chronic active
ADR ID BADD_A02028
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.07      Hepatocellular damage and hepatitis NEC
09.01.07.006      Hepatitis chronic active
11      Infections and infestations
11.07      Ancillary infectious topics
11.07.01      Inflammatory disorders following infection
11.07.01.002      Hepatitis chronic active
Description INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors. | An aggressive form of chronic hepatitis involving extensive liver damage and cell injury beyond the portal tract. | A mild form of chronic hepatitis causing limited damage to the liver. [MeSH]
MedDRA Code 10019755
MeSH ID D006521
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic active hepatitis | Hepatitis chronic active | Hepatitis chronic active (immune) | Hepatitis chronic active aggravated | Hepatitis chronic active aggrav. | Hepatitis, Chronic | Chronic Hepatitis | Cryptogenic Chronic Hepatitis | Chronic Hepatitis, Cryptogenic | Hepatitis, Cryptogenic Chronic | Hepatitis, Chronic, Cryptogenic | Hepatitis, Chronic Active | Chronic Active Hepatitis | Hepatitis, Chronic Persistent | Chronic Persistent Hepatitides | Chronic Persistent Hepatitis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00415Cerivastatin--
BADD_D00948Fluvastatin--
BADD_D00949Fluvastatin sodium--
BADD_D01325Lovastatin--
BADD_D01470Minocycline0.000177%
BADD_D01576Nitrofurantoin--
BADD_D01577Nitrofurantoin (macrocrystals)--
BADD_D01578Nitrofurantoin (monohydrate/macrocrystals)--
BADD_D01824Pravastatin--
BADD_D01825Pravastatin sodium--
BADD_D01989Saquinavir mesylate--
BADD_D02026Simvastatin--
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