Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Herpes simplex encephalitis
ADR ID BADD_A02061
ADR Hierarchy
11      Infections and infestations
11.05      Viral infectious disorders
11.05.02      Herpes viral infections
11.05.02.019      Herpes simplex encephalitis
17      Nervous system disorders
17.06      Central nervous system infections and inflammations
17.06.06      Encephalitis of viral origin
17.06.06.004      Herpes simplex encephalitis
Description An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4) [MeSH]
MedDRA Code 10019953
MeSH ID D020803
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Herpes simplex encephalitis | Herpes simplex encephalomyelitis | Encephalitis, Herpes Simplex | Encephalitides, Herpes Simplex | Herpes Simplex Encephalitides | Herpes Encephalitis | Encephalitis, Herpes | Herpetic Encephalitis | Encephalitides, Herpetic | Encephalitis, Herpetic | Herpetic Encephalitides | Herpes Simplex Encephalitis | Meningoencephalitis, Herpes Simplex Virus | Herpetic Meningoencephalitis | Herpetic Meningoencephalitides | Meningoencephalitides, Herpetic | Meningoencephalitis, Herpetic | Herpes Simplex Meningoencephalitis | Herpes Simplex Meningoencephalitides | Meningoencephalitides, Herpes Simplex | Meningoencephalitis, Herpes Simplex | Herpetic Acute Necrotizing Encephalitis | Acute Necrotizing Encephalitis, Herpetic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00899Fingolimod hydrochloride--
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