Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hydrocephalus
ADR ID BADD_A02099
ADR Hierarchy
17      Nervous system disorders
17.07      Increased intracranial pressure and hydrocephalus
17.07.01      Hydrocephalic conditions
17.07.01.001      Hydrocephalus
Description A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. [CTCAE] Excessive accumulation of cerebrospinal fluid within the cranium which may be associated with dilation of cerebral ventricles, INTRACRANIAL HYPERTENSION; HEADACHE; lethargy; URINARY INCONTINENCE; and ATAXIA. | Enlargement of CEREBRAL VENTRICLES. Although it is often isolated without other CNS anomalies it can be associated with other congenital malformations (e.g., ARNOLD-CHIARI MALFORMATION; DANDY-WALKER MALFORMATION, and ACROCALLOSAL SYNDROME). [MeSH]
MedDRA Code 10020508
MeSH ID D006849
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Communicating hydrocephalus | Hydrocephalus | Hydrocephalus acquired | Hydrocephalus NOS | Hydrocephaly | Hydrocephaly communicative | Hydrocephaly obstructive | Obstructive hydrocephalus | Non-communicating hydrocephalus | Post inflammatory hydrocephalus | Cerebral Ventriculomegaly | Cerebral Ventriculomegalies | Ventriculomegalies, Cerebral | Ventriculomegaly, Cerebral | Communicating Hydrocephalus | Hydrocephalus, Communicating | Congenital Hydrocephalus | Hydrocephalus, Congenital | Hydrocephalus Ex-Vacuo | Hydrocephalus Ex Vacuo | Hydrocephalus Ex-Vacuos | Obstructive Hydrocephalus | Hydrocephalus, Obstructive | Post-Traumatic Hydrocephalus | Hydrocephalus, Post-Traumatic | Post Traumatic Hydrocephalus | Aqueductal Stenosis | Aqueductal Stenoses | Stenoses, Aqueductal | Stenosis, Aqueductal | Fetal Cerebral Ventriculomegaly | Cerebral Ventriculomegalies, Fetal | Cerebral Ventriculomegaly, Fetal | Fetal Cerebral Ventriculomegalies | Ventriculomegalies, Fetal Cerebral | Ventriculomegaly, Fetal Cerebral
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01008Gefitinib0.000112%
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01119Ibrutinib0.000392%
BADD_D01136Imatinib0.000168%
BADD_D01213Isotretinoin0.000515%
BADD_D01236Labetalol0.000163%
BADD_D01243Lamotrigine0.000166%
BADD_D01250Lasofoxifene--
BADD_D01252Leflunomide0.000428%
BADD_D01258Leucovorin0.001239%
BADD_D01265Levetiracetam0.000397%
BADD_D01366Medroxyprogesterone acetate--
BADD_D01380Menotropins--
BADD_D01405Methadone0.001458%
BADD_D01477Misoprostol0.001233%
BADD_D01498Morphine0.000390%
BADD_D01549Nelarabine--
BADD_D01567Nilotinib0.000168%
BADD_D01569Nimodipine0.000117%
BADD_D01599Olanzapine0.000210%
BADD_D01629Osimertinib0.000168%
BADD_D01679Paroxetine0.000407%
BADD_D01687Pazopanib0.000112%
BADD_D01831Prednisolone0.000122%
BADD_D01834Prednisone0.000018%
BADD_D01888Quetiapine0.000055%
BADD_D01954Rivaroxaban0.000982%
BADD_D01966Ropinirole--
BADD_D02010Sertraline0.000038%
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