Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hydrocephalus
ADR ID BADD_A02099
ADR Hierarchy
17      Nervous system disorders
17.07      Increased intracranial pressure and hydrocephalus
17.07.01      Hydrocephalic conditions
17.07.01.001      Hydrocephalus
Description A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. [CTCAE] Excessive accumulation of cerebrospinal fluid within the cranium which may be associated with dilation of cerebral ventricles, INTRACRANIAL HYPERTENSION; HEADACHE; lethargy; URINARY INCONTINENCE; and ATAXIA. | Enlargement of CEREBRAL VENTRICLES. Although it is often isolated without other CNS anomalies it can be associated with other congenital malformations (e.g., ARNOLD-CHIARI MALFORMATION; DANDY-WALKER MALFORMATION, and ACROCALLOSAL SYNDROME). [MeSH]
MedDRA Code 10020508
MeSH ID D006849
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Communicating hydrocephalus | Hydrocephalus | Hydrocephalus acquired | Hydrocephalus NOS | Hydrocephaly | Hydrocephaly communicative | Hydrocephaly obstructive | Obstructive hydrocephalus | Non-communicating hydrocephalus | Post inflammatory hydrocephalus | Cerebral Ventriculomegaly | Cerebral Ventriculomegalies | Ventriculomegalies, Cerebral | Ventriculomegaly, Cerebral | Communicating Hydrocephalus | Hydrocephalus, Communicating | Congenital Hydrocephalus | Hydrocephalus, Congenital | Hydrocephalus Ex-Vacuo | Hydrocephalus Ex Vacuo | Hydrocephalus Ex-Vacuos | Obstructive Hydrocephalus | Hydrocephalus, Obstructive | Post-Traumatic Hydrocephalus | Hydrocephalus, Post-Traumatic | Post Traumatic Hydrocephalus | Aqueductal Stenosis | Aqueductal Stenoses | Stenoses, Aqueductal | Stenosis, Aqueductal | Fetal Cerebral Ventriculomegaly | Cerebral Ventriculomegalies, Fetal | Cerebral Ventriculomegaly, Fetal | Fetal Cerebral Ventriculomegalies | Ventriculomegalies, Fetal Cerebral | Ventriculomegaly, Fetal Cerebral
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02066Spironolactone0.000037%
BADD_D02105Tacrolimus0.000743%
BADD_D02150Temozolomide0.000504%
BADD_D02192Thalidomide0.000482%
BADD_D02214Ticagrelor0.000408%
BADD_D02246Tolvaptan0.000058%
BADD_D02257Trametinib0.000168%
BADD_D02272Triamcinolone acetonide--
BADD_D02319Urofollitropin--
BADD_D02329Valproic acid0.000749%
BADD_D02344Vemurafenib0.000112%
BADD_D02355Vigabatrin0.000125%
BADD_D02370Vorinostat0.000112%
BADD_D02373Warfarin0.000505%
BADD_D02392Zoledronic acid--
BADD_D02464Fingolimod0.000844%
BADD_D02603Tucatinib0.000168%
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