Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hyperlactacidaemia
ADR ID BADD_A02128
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.01      Metabolic acidoses (excl diabetic acidoses)
14.01.01.006      Hyperlactacidaemia
Description Increase in blood LACTATE concentration often associated with SEPTIC SHOCK; LUNG INJURY; SEPSIS; and DRUG TOXICITY. When hyperlactatemia is associated with low body pH (acidosis) it is LACTIC ACIDOSIS. [MeSH]
MedDRA Code 10020660
MeSH ID D065906
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hyperlactacidaemia | Hyperlactacidemia | Symptomatic hyperlactataemia | Asymptomatic hyperlactataemia | Hyperlactatemia | Symptomatic hyperlactatemia | Hyperlactataemia | Asymptomatic hyperlactatemia | Hyperlactatemias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01656Paliperidone0.004644%
BADD_D01765Phenytoin0.000191%
BADD_D01856Propafenone--
BADD_D01864Propofol0.000357%
BADD_D01888Quetiapine0.000055%
BADD_D01933Ribavirin--
BADD_D01989Saquinavir mesylate--
BADD_D02028Sirolimus--
BADD_D02066Spironolactone0.000037%
BADD_D02068Stavudine0.000565%
BADD_D02105Tacrolimus--
BADD_D02155Tenofovir disoproxil--
BADD_D02329Valproic acid0.000619%
BADD_D02373Warfarin0.000056%
BADD_D02383Zidovudine0.006631%
BADD_D02394Zolpidem0.000025%
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