Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hyperprolactinaemia
ADR ID BADD_A02141
ADR Hierarchy
05      Endocrine disorders
05.03      Hypothalamus and pituitary gland disorders
05.03.01      Anterior pituitary hyperfunction
05.03.01.002      Hyperprolactinaemia
Description Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8) [MeSH]
MedDRA Code 10020737
MeSH ID D006966
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hyperprolactinaemia | Hyperprolactinaemia aggravated | Hyperprolactinemia | Hyperprolactinemia aggravated | Hyperprolactinemias | Prolactin, Inappropriate Secretion | Inappropriate Secretion Prolactin | Secretion Prolactin, Inappropriate | Inappropriate Prolactin Secretion Syndrome | Prolactin Hypersecretion Syndrome | Hypersecretion Syndrome, Prolactin | Syndrome, Prolactin Hypersecretion | Inappropriate Prolactin Secretion | Prolactin Secretion, Inappropriate | Secretion, Inappropriate Prolactin
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam--
BADD_D00165Aripiprazole0.000840%
BADD_D00172Asenapine--
BADD_D00305Bromocriptine mesylate--
BADD_D00329Cabergoline0.004804%
BADD_D00356Carbamazepine0.000186%
BADD_D00369Cariprazine0.000444%
BADD_D00475Citalopram--
BADD_D00476Citalopram hydrobromide--
BADD_D00511Clozapine0.007949%
BADD_D00648Diazepam0.000050%
BADD_D00731Droperidol--
BADD_D00734Duloxetine0.000162%
BADD_D00735Duloxetine hydrochloride--
BADD_D00736Dutasteride0.000501%
BADD_D00809Escitalopram0.000047%
BADD_D00810Escitalopram oxalate--
BADD_D00932Fluoxetine0.000240%
BADD_D00933Fluoxetine hydrochloride--
BADD_D00950Fluvoxamine--
BADD_D01054Haloperidol--
BADD_D01245Lansoprazole0.000268%
BADD_D01301Lisuride--
BADD_D01330Lurasidone0.000656%
BADD_D01425Methyldopa--
BADD_D01426Methyldopate hydrochloride--
BADD_D01442Metoclopramide--
BADD_D01466Milnacipran hydrochloride--
BADD_D01476Mirtazapine0.000080%
BADD_D01599Olanzapine0.011261%
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