Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hyperthyroidism
ADR ID BADD_A02157
ADR Hierarchy
05      Endocrine disorders
05.02      Thyroid gland disorders
05.02.02      Thyroid hyperfunction disorders
05.02.02.001      Hyperthyroidism
14      Metabolism and nutrition disorders
14.11      Metabolism disorders NEC
14.11.01      Metabolic disorders NEC
14.11.01.011      Hyperthyroidism
Description A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose. [CTCAE] Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE. [MeSH]
MedDRA Code 10020850
MeSH ID D006980; D013971
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hyperthyroidism | Hyperthyroidism aggravated | Thyrotoxicosis | Thyrotoxicosis aggravated | Thyrotoxicosis from ectopic thyroid nodule | Thyrotoxicosis from ectopic thyroid nodule without mention of thyrotoxic crisis or storm | Thyrotoxicosis of other specified origin | Thyrotoxicosis of other specified origin without mention of thyrotoxic crisis or storm | Thyrotoxicosis with or without goiter | Thyrotoxicosis with or without goitre | Thyrotoxicosis without goitre | Thyrotoxicosis without mention of goiter or other cause | Thyrotoxicosis without mention of goiter or other cause, and w/o ment of thyrotoxic crisis or storm | Thyrotoxicosis without mention of goitre or other cause | Latent hyperthyroidism | Iodine hyperthyroidism | Subclinical hyperthyroidism | Thyrotoxicosis without goiter | Drug-induced thyrotoxicosis | Thyroid function increased | Thyrotoxicosis factitia | Hyperthyreosis | Hyperthyroid | Hyperthyroids | Primary Hyperthyroidism | Hyperthyroidism, Primary
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01213Isotretinoin--
BADD_D01236Labetalol--
BADD_D01243Lamotrigine0.000166%
BADD_D01245Lansoprazole0.000249%
BADD_D01252Leflunomide0.001500%
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib0.000839%
BADD_D01257Letrozole0.000263%
BADD_D01271Levocarnitine0.012937%
BADD_D01285Levothyroxine0.000369%
BADD_D01286Levothyroxine sodium--
BADD_D01296Liothyronine0.001969%
BADD_D01303Lithium carbonate0.002142%
BADD_D01304Lithium cation0.001056%
BADD_D01305Lithium hydroxide--
BADD_D01322Losartan0.000020%
BADD_D01366Medroxyprogesterone acetate--
BADD_D01378Memantine--
BADD_D01397Mesalamine0.000183%
BADD_D01401Metformin0.000034%
BADD_D01414Methimazole0.001658%
BADD_D01431Methylphenidate0.000206%
BADD_D01445Metoprolol0.000013%
BADD_D01470Minocycline0.003778%
BADD_D01533Naproxen--
BADD_D01567Nilotinib0.000560%
BADD_D01581Nivolumab--
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
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