Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hypogammaglobulinaemia
ADR ID BADD_A02186
ADR Hierarchy
10      Immune system disorders
10.03      Immunodeficiency syndromes
10.03.02      Immunodeficiency disorders NEC
10.03.02.007      Hypogammaglobulinaemia
Description An immunologic deficiency state characterized by an extremely low level of generally all classes of gamma-globulin in the blood. [MeSH]
MedDRA Code 10020983
MeSH ID D000361
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Agammaglobulinaemia | Agammaglobulinemia | Hypogammaglobulinaemia | Hypogammaglobulinaemia NOS | Hypogammaglobulinemia, unspecified | Other selective immunoglobulin deficiencies | Physiologic hypogammaglobulinemia | Transient hypogammaglobulinemia | Hypogammaglobulinemia | Hypogammaglobulinaemia, unspecified | Physiologic hypogammaglobulinaemia | Transient hypogammaglobulinaemia | Panhypogammaglobulinaemia | Panhypogammaglobulinemia | Hypoimmunoglobulinemia | Hypoimmunoglobulinaemia | Agammaglobulinemias | Hypogammaglobulinemias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D00195Azathioprine0.000470%
BADD_D00230Bendamustine0.000448%
BADD_D00318Busulfan--
BADD_D00356Carbamazepine0.001302%
BADD_D00367Carfilzomib0.000112%
BADD_D00511Clozapine0.017732%
BADD_D00551Cyclosporine0.000276%
BADD_D00589Dasatinib0.000224%
BADD_D00623Dexamethasone0.000291%
BADD_D00858Everolimus0.000153%
BADD_D00914Fludarabine0.000280%
BADD_D00981Gabapentin0.000021%
BADD_D01119Ibrutinib0.001511%
BADD_D01130Idelalisib0.000280%
BADD_D01136Imatinib0.000280%
BADD_D01243Lamotrigine0.000745%
BADD_D01252Leflunomide0.000857%
BADD_D01257Letrozole0.000263%
BADD_D01265Levetiracetam0.000596%
BADD_D01295Linezolid0.007410%
BADD_D01392Mercaptopurine0.004164%
BADD_D01418Methotrexate--
BADD_D01419Methotrexate sodium--
BADD_D01567Nilotinib0.000168%
BADD_D01637Oxcarbazepine0.000596%
BADD_D01765Phenytoin0.000191%
BADD_D01799Ponatinib0.000168%
BADD_D01831Prednisolone0.000122%
BADD_D01834Prednisone0.000063%
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