Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypoglycaemia
ADR ID BADD_A02189
ADR Hierarchy
05      Endocrine disorders
05.06      Glucose metabolism disorders (incl diabetes mellitus)
05.06.03      Hypoglycaemic conditions NEC
05.06.03.001      Hypoglycaemia
14      Metabolism and nutrition disorders
14.06      Glucose metabolism disorders (incl diabetes mellitus)
14.06.03      Hypoglycaemic conditions NEC
14.06.03.001      Hypoglycaemia
Description A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH. | HYPOGLYCEMIA expressed after a meal or FOOD INTAKE. It is also called reactive or stimulative hypoglycemia. | HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast. [MeSH]
MedDRA Code 10020993
MeSH ID D007003
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hypoglycaemia | Hypoglycaemia night | Hypoglycaemia NOS | Hypoglycaemia, unspecified | Hypoglycaemic attack | Hypoglycaemic reaction | Hypoglycemia | Hypoglycemia, unspecified | Hypoglycemic reaction | Hypos | Other specified hypoglycemia | Protoracted hypoglycaemia | Reaction hypoglycemic | Hypoglycaemia aggravated | Hypoglycemic episode | Hypoglycemia aggravated | Ketotic hypoglycaemia | Ketotic hypoglycemia | Hypoglycaemic episode | Reaction hypoglycaemic | Hypoglycemia night | Hypoglycemic attack | Asymptomatic hypoglycemia | Asymptomatic hypoglycaemia | Fasting hypoglycaemia | Fasting hypoglycemia | Severe hypoglycaemia | Severe hypoglycemia | Postprandial Hypoglycemia | Hypoglycemia, Postprandial | Reactive Hypoglycemia | Hypoglycemia, Reactive | Fasting Hypoglycemia | Hypoglycemia, Fasting | Postabsorptive Hypoglycemia | Hypoglycemia, Postabsorptive
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00178Atenolol0.000107%
BADD_D00180Atomoxetine--
BADD_D00182Atorvastatin calcium--
BADD_D00186Atovaquone--
BADD_D00189Atropine--
BADD_D00190Atropine sulfate--
BADD_D00192Avanafil--
BADD_D00193Axitinib--
BADD_D00214Basiliximab--
BADD_D00229Benazeprilat-
BADD_D00263Betaxolol--
BADD_D00271Bicalutamide0.002812%
BADD_D00277Bisoprolol0.003297%
BADD_D00285Bosentan--
BADD_D00305Bromocriptine mesylate--
BADD_D00312Bupropion--
BADD_D00313Bupropion hydrobromide--
BADD_D00314Bupropion hydrochloride--
BADD_D00330Cabozantinib0.001892%
BADD_D00332Caffeine0.000092%
BADD_D00333Caffeine citrate--
BADD_D00344Canagliflozin0.007484%
BADD_D00347Candesartan cilexetil0.002944%
BADD_D00354Captopril0.000488%
BADD_D00356Carbamazepine--
BADD_D00372Carteolol--
BADD_D00373Carteolol hydrochloride--
BADD_D00374Carvedilol0.000087%
BADD_D00375Carvedilol phosphate--
BADD_D00386Cefepime0.000049%
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ADReCS-Target
ADR Term Drug Name Target