Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hypoglycaemia
ADR ID BADD_A02189
ADR Hierarchy
05      Endocrine disorders
05.06      Glucose metabolism disorders (incl diabetes mellitus)
05.06.03      Hypoglycaemic conditions NEC
05.06.03.001      Hypoglycaemia
14      Metabolism and nutrition disorders
14.06      Glucose metabolism disorders (incl diabetes mellitus)
14.06.03      Hypoglycaemic conditions NEC
14.06.03.001      Hypoglycaemia
Description A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH. | HYPOGLYCEMIA expressed after a meal or FOOD INTAKE. It is also called reactive or stimulative hypoglycemia. | HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast. [MeSH]
MedDRA Code 10020993
MeSH ID D007003
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hypoglycaemia | Hypoglycaemia night | Hypoglycaemia NOS | Hypoglycaemia, unspecified | Hypoglycaemic attack | Hypoglycaemic reaction | Hypoglycemia | Hypoglycemia, unspecified | Hypoglycemic reaction | Hypos | Other specified hypoglycemia | Protoracted hypoglycaemia | Reaction hypoglycemic | Hypoglycaemia aggravated | Hypoglycemic episode | Hypoglycemia aggravated | Ketotic hypoglycaemia | Ketotic hypoglycemia | Hypoglycaemic episode | Reaction hypoglycaemic | Hypoglycemia night | Hypoglycemic attack | Asymptomatic hypoglycemia | Asymptomatic hypoglycaemia | Fasting hypoglycaemia | Fasting hypoglycemia | Severe hypoglycaemia | Severe hypoglycemia | Postprandial Hypoglycemia | Hypoglycemia, Postprandial | Reactive Hypoglycemia | Hypoglycemia, Reactive | Fasting Hypoglycemia | Hypoglycemia, Fasting | Postabsorptive Hypoglycemia | Hypoglycemia, Postabsorptive
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00994Gadoversetamide--
BADD_D01006Gatifloxacin--
BADD_D01015Gemtuzumab ozogamicin--
BADD_D01022Gliclazide--
BADD_D01023Glimepiride0.003681%
BADD_D01024Glipizide0.002606%
BADD_D01025Glucagon--
BADD_D01026Glucagon hydrochloride--
BADD_D01030Glyburide0.002417%
BADD_D01051Halobetasol--
BADD_D01054Haloperidol--
BADD_D01055Haloperidol decanoate--
BADD_D01056Haloperidol lactate--
BADD_D01081Hydralazine0.000136%
BADD_D01083Hydrochlorothiazide0.000015%
BADD_D01086Hydrocortisone0.000125%
BADD_D01103Hydroxychloroquine0.010598%
BADD_D01110Hydroxyurea0.000358%
BADD_D01120Ibuprofen0.000009%
BADD_D01121Ibuprofen lysine--
BADD_D01124Icodextrin--
BADD_D01130Idelalisib--
BADD_D01136Imatinib--
BADD_D01154Indium in-111 pentetreotide--
BADD_D01156Indomethacin--
BADD_D01159Insulin (human)--
BADD_D01160Insulin aspart--
BADD_D01161Insulin degludec--
BADD_D01162Insulin detemir--
BADD_D01163Insulin glargine--
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ADReCS-Target
ADR Term Drug Name Target