Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypoglycaemic coma
ADR ID BADD_A02191
ADR Hierarchy
05      Endocrine disorders
05.06      Glucose metabolism disorders (incl diabetes mellitus)
05.06.03      Hypoglycaemic conditions NEC
05.06.03.004      Hypoglycaemic coma
14      Metabolism and nutrition disorders
14.06      Glucose metabolism disorders (incl diabetes mellitus)
14.06.03      Hypoglycaemic conditions NEC
14.06.03.004      Hypoglycaemic coma
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.09      Coma states
17.02.09.005      Hypoglycaemic coma
Description Severe HYPOGLYCEMIA induced by a large dose of exogenous INSULIN resulting in a COMA or profound state of unconsciousness from which the individual cannot be aroused. | Sudden significant drop in BLOOD GLUCOSE or hypoglycemic shock which affects the hemodynamic equilibrium of all vital organs. [MeSH]
MedDRA Code 10021000
MeSH ID D007331
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Coma hypoglycaemic | Coma hypoglycemic | Hypoglycaemic coma | Hypoglycemic coma | Insulin coma | Diabetic hypoglycemic coma | Diabetic hypoglycaemic coma | Insulin Coma | Coma, Insulin | Insulin Shock | Shock, Insulin
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00018Acarbose0.002167%
BADD_D00121Amlodipine0.000006%
BADD_D00277Bisoprolol0.001413%
BADD_D00354Captopril0.000732%
BADD_D00480Clarithromycin0.000223%
BADD_D00578Dapagliflozin0.000877%
BADD_D00706Donepezil0.000070%
BADD_D00765Empagliflozin--
BADD_D00979Furosemide0.000021%
BADD_D01006Gatifloxacin--
BADD_D01022Gliclazide--
BADD_D01023Glimepiride0.001019%
BADD_D01024Glipizide0.000181%
BADD_D01025Glucagon--
BADD_D01026Glucagon hydrochloride--
BADD_D01124Icodextrin--
BADD_D01159Insulin (human)--
BADD_D01160Insulin aspart--
BADD_D01162Insulin detemir--
BADD_D01245Lansoprazole0.000149%
BADD_D01275Levofloxacin0.000084%
BADD_D01292Linagliptin0.000243%
BADD_D01401Metformin0.000198%
BADD_D01414Methimazole--
BADD_D01533Naproxen0.000019%
BADD_D01599Olanzapine0.000210%
BADD_D01668Pantoprazole0.000016%
BADD_D01777Pioglitazone0.000129%
BADD_D01835Pregabalin0.000130%
BADD_D01867Propranolol0.000267%
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