Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypoparathyroidism
ADR ID BADD_A02204
ADR Hierarchy
05      Endocrine disorders
05.04      Parathyroid gland disorders
05.04.02      Hypoparathyroid disorders
05.04.02.001      Hypoparathyroidism
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.15      Endocrine procedural complications
12.02.15.001      Hypoparathyroidism
14      Metabolism and nutrition disorders
14.04      Bone, calcium, magnesium and phosphorus metabolism disorders
14.04.01      Calcium metabolism disorders
14.04.01.007      Hypoparathyroidism
Description A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. [CTCAE] A condition caused by a deficiency of PARATHYROID HORMONE (or PTH). It is characterized by HYPOCALCEMIA and hyperphosphatemia. Hypocalcemia leads to TETANY. The acquired form is due to removal or injuries to the PARATHYROID GLANDS. The congenital form is due to mutations of genes, such as TBX1; (see DIGEORGE SYNDROME); CASR encoding CALCIUM-SENSING RECEPTOR; or PTH encoding parathyroid hormone. | A condition of low or absent PTH level and HYPOCALCEMIA. It usually occurs as part of an autoimmune syndrome. [MeSH]
MedDRA Code 10021041
MeSH ID D007011
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hypoparathyroidism | Idiopathic Hypoparathyroidism | Hypoparathyroidism, Idiopathic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000132%
BADD_D00102Amifostine--
BADD_D00178Atenolol0.000019%
BADD_D00337Calcitriol--
BADD_D00364Carboplatin0.000224%
BADD_D00474Cisplatin0.000168%
BADD_D00869Famotidine0.000250%
BADD_D01095Hydrogen iodide--
BADD_D01668Pantoprazole0.000098%
BADD_D01676Paricalcitol--
BADD_D01833Prednisolone sodium phosphate--
BADD_D02329Valproic acid--
BADD_D02434Cinacalcet0.000586%
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