Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypopituitarism
ADR ID BADD_A02207
ADR Hierarchy
05      Endocrine disorders
05.03      Hypothalamus and pituitary gland disorders
05.03.02      Anterior pituitary hypofunction
05.03.02.001      Hypopituitarism
Description A disorder characterized by a decrease in production of hormones from the pituitary gland. [CTCAE] Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions. [MeSH]
MedDRA Code 10021067
MeSH ID D007018
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hypopituitalism | Hypopituitarism | Insufficiency pituitary | Panhypopituitarism | Pituitary activity decreased | Pituitary function depression | Pituitary hormone deficiency | Pituitary insufficiency | Pituitary Insufficiency | Insufficiency, Pituitary | Hyposecretion Syndrome, Anterior Pituitary | Hyposecretion, Adenohypophyseal | Adenohypophyseal Hyposecretion | Anterior Pituitary Hyposecretion Syndrome | Postpartum Hypopituitarism | Hypopituitarism, Postpartum | Simmonds' Disease | Simmond's Disease | Sheehan Syndrome | Syndrome, Sheehan | Postpartum Panhypopituitarism | Panhypopituitarism, Postpartum | Postpartum Pituitary Insufficiency | Pituitary Insufficiency, Postpartum | Sheehan's Syndrome | Sheehans Syndrome | Syndrome, Sheehan's | Simmonds Disease | Disease, Simmonds
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01952Ritonavir0.000735%
BADD_D02010Sertraline0.000045%
BADD_D02192Thalidomide0.000241%
BADD_D02203Thiotepa--
BADD_D02272Triamcinolone acetonide--
BADD_D02273Triamcinolone diacetate--
BADD_D02274Triamcinolone hexacetonide--
BADD_D02473Sodium chloride--
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