Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Irritability
ADR ID BADD_A02415
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.011      Irritability
19      Psychiatric disorders
19.04      Mood disorders and disturbances NEC
19.04.02      Emotional and mood disturbances NEC
19.04.02.013      Irritability
Description A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition. [CTCAE] Abnormal or excessive excitability with easily triggered anger, annoyance, or impatience. [MeSH]
MedDRA Code 10022998
MeSH ID D007508
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Erethism | Feeling irritated | Irritability | Irritable | Irritable excitation | Irritable sensation transient | Irritable symptom | Slightly irritable | Snappy | Irritable mood | Irritable Mood | Mood, Irritable | Irritable Moods | Moods, Irritable
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01168Interferon alfacon-1--
BADD_D01181Iopamidol--
BADD_D01204Isoniazid--
BADD_D01209Isosorbide--
BADD_D01213Isotretinoin0.018242%
BADD_D01234Ketotifen--
BADD_D01236Labetalol0.000244%
BADD_D01238Lacosamide0.026181%
BADD_D01243Lamotrigine0.001805%
BADD_D01257Letrozole--
BADD_D01260Leuprolide acetate--
BADD_D01265Levetiracetam0.009158%
BADD_D01277Levomefolate calcium--
BADD_D01281Levonorgestrel0.053992%
BADD_D01285Levothyroxine0.000396%
BADD_D01286Levothyroxine sodium--
BADD_D01287Lidocaine--
BADD_D01299Lisdexamfetamine dimesylate--
BADD_D01300Lisinopril--
BADD_D01303Lithium carbonate0.001338%
BADD_D01317Loratadine--
BADD_D01318Lorazepam0.000206%
BADD_D01321Lormetazepam--
BADD_D01322Losartan--
BADD_D01325Lovastatin0.000112%
BADD_D01330Lurasidone0.005345%
BADD_D01365Medroxyprogesterone--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01369Mefloquine--
BADD_D01373Melatonin0.000465%
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