Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Keratoconus
ADR ID BADD_A02443
ADR Hierarchy
06      Eye disorders
06.06      Anterior eye structural change, deposit and degeneration
06.06.03      Corneal structural change, deposit and degeneration
06.06.03.017      Keratoconus
Description A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed) [MeSH]
MedDRA Code 10023353
MeSH ID D007640
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Keratoconus | Keratoconus, acute hydrops | Keratoconus, stable condition | Keratoconus, unspecified
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00809Escitalopram--
BADD_D01213Isotretinoin0.001467%
BADD_D01251Latanoprost0.000045%
BADD_D01290Lifitegrast0.000401%
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