Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Large intestine perforation
ADR ID BADD_A02475
ADR Hierarchy
07      Gastrointestinal disorders
07.04      Gastrointestinal ulceration and perforation
07.04.06      Intestinal ulcers and perforation NEC
07.04.06.005      Large intestine perforation
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.03      Gastrointestinal and hepatobiliary procedural complications
12.02.03.005      Large intestine perforation
Description Not Available
MedDRA Code 10023804
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Colon perforation | Colonic perforation | Intestinal perforation large | Large bowel perforation | Large intestinal perforation NOS | Large intestine perforation | Perforated colon | Perforated large intestine | Perforation colon | Perforation large intestine | Perforation of colon | Ruptured diverticulum of colon | Caecum perforation | Caecum rupture | Cecum perforation | Cecum rupture
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02100Sunitinib0.000224%
BADD_D02105Tacrolimus0.000594%
BADD_D02192Thalidomide0.000482%
BADD_D02236Tofacitinib0.002170%
BADD_D02272Triamcinolone acetonide--
BADD_D02274Triamcinolone hexacetonide--
BADD_D02344Vemurafenib0.000112%
BADD_D02373Warfarin0.000056%
BADD_D02445Solifenacin0.000174%
BADD_D02462Methylnaltrexone0.000659%
BADD_D02470Nintedanib0.000168%
BADD_D02474Carbon dioxide0.001239%
BADD_D02487Baricitinib0.000241%
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