Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Laryngospasm
ADR ID BADD_A02487
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.04      Upper respiratory tract disorders (excl infections)
22.04.02      Laryngeal spasm, oedema and obstruction
22.04.02.002      Laryngospasm
Description A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. [CTCAE] A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration. [MeSH]
MedDRA Code 10023891
MeSH ID D007826
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Glottic spasm | Laryngeal spasm | Laryngismus | Laryngospasm | Larynx muscle hypersensitive | Spasm glottis | Spasm larynx | Laryngospasms | Laryngeal Spasm | Laryngeal Spasms | Spasm, Laryngeal | Spasms, Laryngeal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000064r,6r-dorzolamide--
BADD_D00016Acamprosate--
BADD_D00017Acamprosate calcium--
BADD_D00019Acebutolol--
BADD_D00020Acebutolol hydrochloride--
BADD_D00067Alfentanil--
BADD_D00068Alfentanil hydrochloride--
BADD_D00077Almotriptan--
BADD_D00078Almotriptan malate--
BADD_D00129Amoxicillin0.000007%
BADD_D00133Ampicillin--
BADD_D00165Aripiprazole--
BADD_D00166Aripiprazole lauroxil--
BADD_D00178Atenolol--
BADD_D00187Atracurium--
BADD_D00188Atracurium besylate--
BADD_D00189Atropine--
BADD_D00190Atropine sulfate--
BADD_D00240Benzonatate--
BADD_D00263Betaxolol--
BADD_D00269Bexarotene--
BADD_D00277Bisoprolol--
BADD_D00278Bisoprolol fumarate--
BADD_D00308Bupivacaine--
BADD_D00349Capecitabine0.000783%
BADD_D00364Carboplatin0.000560%
BADD_D00376Caspofungin--
BADD_D00445Chlorpromazine--
BADD_D00473Cisatracurium besylate--
BADD_D00499Clomipramine--
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