Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Leukoencephalopathy
ADR ID BADD_A02520
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.02      Encephalopathies NEC
17.13.02.003      Leukoencephalopathy
Description A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. [CTCAE] Any of various diseases affecting the white matter of the central nervous system. [MeSH]
MedDRA Code 10024382
MeSH ID D056784
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Leukoencephalopathy | Disseminated necrotizing leukoencephalopathy | Disseminated necrotising leukoencephalopathy | Leukoencephalopathies | White Matter Diseases | Disease, White Matter | Diseases, White Matter | White Matter Disease | Childhood Ataxia with Central Nervous System Hypomyelinization | Leukoencephalopathy with Vanishing White Matter | Childhood Ataxia with Diffuse Central Nervous System Hypomyelination | Vanishing White Matter Leukodystrophy | Cree Leukoencephalopathy | Cree Leukoencephalopathies | Leukoencephalopathies, Cree | Leukoencephalopathy, Cree | Childhood Ataxia with Central Nervous System Hypomyelination | CACH Syndrome | CACH Syndromes | Syndrome, CACH | Syndromes, CACH | Myelinosis Centralis Diffusa | Centralis Diffusa, Myelinosis | Centralis Diffusas, Myelinosis | Diffusa, Myelinosis Centralis | Diffusas, Myelinosis Centralis | Myelinosis Centralis Diffusas | CACH VWM Syndrome | CACH VWM Syndromes | Syndrome, CACH VWM | Syndromes, CACH VWM | VWM Syndrome, CACH | VWM Syndromes, CACH
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01405Methadone0.005303%
BADD_D01418Methotrexate0.003013%
BADD_D01419Methotrexate sodium--
BADD_D01449Metronidazole0.000144%
BADD_D01476Mirtazapine0.000120%
BADD_D01498Morphine0.001504%
BADD_D01549Nelarabine0.000112%
BADD_D01567Nilotinib0.000112%
BADD_D01629Osimertinib0.000224%
BADD_D01633Oxaliplatin0.000448%
BADD_D01645Oxycodone0.000186%
BADD_D01653Paclitaxel0.000168%
BADD_D01687Pazopanib0.000112%
BADD_D01831Prednisolone0.000035%
BADD_D01886Pyrimethamine0.000142%
BADD_D01933Ribavirin0.007912%
BADD_D02058Sorafenib0.000168%
BADD_D02100Sunitinib0.000616%
BADD_D02105Tacrolimus0.002079%
BADD_D02254Tramadol0.000014%
The 2th Page    First    Pre   2    Total 2 Pages