Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01230Ketoconazole--
BADD_D01231Ketoprofen--
BADD_D01232Ketorolac0.000708%
BADD_D01233Ketorolac tromethamine--
BADD_D01236Labetalol--
BADD_D01240Lactulose0.002255%
BADD_D01241Lamisil--
BADD_D01242Lamivudine--
BADD_D01243Lamotrigine--
BADD_D01244Lanreotide acetate--
BADD_D01245Lansoprazole0.002814%
BADD_D01252Leflunomide0.006384%
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib0.015390%
BADD_D01255Lercanidipine--
BADD_D01257Letrozole--
BADD_D01258Leucovorin--
BADD_D01259Leucovorin calcium--
BADD_D01260Leuprolide acetate0.076864%
BADD_D01261Leuprolide monoacetate--
BADD_D01262Levalbuterol0.000655%
BADD_D01265Levetiracetam--
BADD_D01272Levocetirizine0.000570%
BADD_D01275Levofloxacin--
BADD_D01276Levoleucovorin--
BADD_D01282Levorphanol-
BADD_D01285Levothyroxine0.000843%
BADD_D01287Lidocaine0.000251%
BADD_D01296Liothyronine0.002492%
BADD_D01298Liraglutide--
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