Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01510Nabilone--
BADD_D01511Nabumetone--
BADD_D01515Nafcillin--
BADD_D01516Nafcillin sodium--
BADD_D01522Nalmefene--
BADD_D01527Naltrexone--
BADD_D01528Naltrexone hydrochloride--
BADD_D01533Naproxen0.000147%
BADD_D01534Naproxen sodium--
BADD_D01535Naratriptan--
BADD_D01536Naratriptan hydrochloride--
BADD_D01541Nebivolol0.000585%
BADD_D01546Nefazodone--
BADD_D01547Nefazodone hydrochloride--
BADD_D01550Nelfinavir mesylate--
BADD_D01555Nepafenac0.001647%
BADD_D01557Nevirapine--
BADD_D01558Nexium--
BADD_D01560Nicardipine--
BADD_D01562Nicorandil--
BADD_D01564Nicotine0.014167%
BADD_D01566Nifedipine--
BADD_D01567Nilotinib--
BADD_D01568Nilutamide--
BADD_D01570Nisoldipine--
BADD_D01571Nitazoxanide--
BADD_D01573Nitrazepam--
BADD_D01576Nitrofurantoin--
BADD_D01578Nitrofurantoin (monohydrate/macrocrystals)--
BADD_D01585Norethindrone0.000533%
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