Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01587Norfloxacin--
BADD_D01588Nortriptyline--
BADD_D01589Nortriptyline hydrochloride--
BADD_D01590Nuvaring--
BADD_D01592Obeticholic acid0.054000%
BADD_D01595Octreotide acetate--
BADD_D01598Ofloxacin--
BADD_D01599Olanzapine--
BADD_D01601Olaparib0.004824%
BADD_D01602Olmesartan--
BADD_D01605Olopatadine--
BADD_D01609Omacetaxine mepesuccinate--
BADD_D01611Omega-3-acid ethyl esters--
BADD_D01614Omeprazole--
BADD_D01615Omeprazole magnesium--
BADD_D01616Onabotulinumtoxina--
BADD_D01617Ondansetron--
BADD_D01618Ondansetron hydrochloride--
BADD_D01621Optimark--
BADD_D01624Orlistat0.032235%
BADD_D01631Oxacillin--
BADD_D01632Oxacillin sodium--
BADD_D01633Oxaliplatin0.010588%
BADD_D01635Oxaprozin0.004054%
BADD_D01636Oxazepam0.003800%
BADD_D01637Oxcarbazepine0.003321%
BADD_D01643Oxybutynin0.000316%
BADD_D01645Oxycodone--
BADD_D01646Oxycodone hydrochloride--
BADD_D01653Paclitaxel0.009503%
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