Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02446Prasterone0.014812%
BADD_D02449Milnacipran0.001951%
BADD_D02452Icatibant-
BADD_D02453Midostaurin--
BADD_D02457Dexmethylphenidate0.001790%
BADD_D02463Pitavastatin0.003421%
BADD_D02464Fingolimod0.100231%
BADD_D02465Aclidinium0.003516%
BADD_D02466Levomilnacipran0.000212%
BADD_D02470Nintedanib--
BADD_D02471Oxygen0.004956%
BADD_D02473Sodium chloride--
BADD_D02482Acalabrutinib--
BADD_D02483Ribociclib0.003212%
BADD_D02484Istradefylline0.015960%
BADD_D02485Talazoparib0.000627%
BADD_D02487Baricitinib0.006052%
BADD_D02489Neratinib0.001757%
BADD_D02490Apalutamide0.008475%
BADD_D02492Deflazacort0.003165%
BADD_D02495Duvelisib0.000548%
BADD_D02497Avatrombopag0.002835%
BADD_D02498Abemaciclib--
BADD_D02499Fostamatinib0.002446%
BADD_D02503Telotristat ethyl-
BADD_D02504Lorlatinib--
BADD_D02509Brigatinib0.001276%
BADD_D02510Rucaparib0.019028%
BADD_D02511Siponimod0.011839%
BADD_D02512Secnidazole0.001204%
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