Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00701Dofetilide0.001937%
BADD_D00702Dolasetron--
BADD_D00704Dolutegravir sodium0.002625%
BADD_D00706Donepezil--
BADD_D00707Donepezil hydrochloride--
BADD_D00711Dornase alfa--
BADD_D00718Doxazosin0.000620%
BADD_D00719Doxazosin mesylate--
BADD_D00720Doxepin--
BADD_D00722Doxercalciferol0.039130%
BADD_D00723Doxorubicin--
BADD_D00725Doxycycline0.000093%
BADD_D00729Dronabinol0.017544%
BADD_D00732Droxidopa0.025525%
BADD_D00733Dulaglutide--
BADD_D00734Duloxetine--
BADD_D00735Duloxetine hydrochloride--
BADD_D00736Dutasteride0.001639%
BADD_D00743Edetate calcium disodium--
BADD_D00745Edetic acid--
BADD_D00749Efavirenz--
BADD_D00755Eletriptan0.009252%
BADD_D00756Eletriptan hydrobromide--
BADD_D00757Eliglustat0.037949%
BADD_D00759Eltrombopag--
BADD_D00765Empagliflozin0.008218%
BADD_D00766Emtricitabine--
BADD_D00768Enalaprilat0.023706%
BADD_D00769Encainide hydrochloride--
BADD_D00771Enfuvirtide--
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