Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Malignant hypertension
ADR ID BADD_A02649
ADR Hierarchy
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.01      Accelerated and malignant hypertension
24.08.01.002      Malignant hypertension
Description A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction. [MeSH]
MedDRA Code 10025600
MeSH ID D006974
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Essential hypertension, malignant | Hypertension malignant | Malignant essential hypertension | Malignant hypertension | Malignant hypertension NOS | Malignant secondary hypertension | Malignant secondary hypertension NOS | Other malignant secondary hypertension | Secondary hypertension, malignant | Hypertension, Malignant | Malignant Hypertension
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D00178Atenolol0.000019%
BADD_D00330Cabozantinib--
BADD_D00367Carfilzomib0.000224%
BADD_D00611Desflurane--
BADD_D00886Ferrosoferric oxide--
BADD_D01009Gemcitabine0.000112%
BADD_D01252Leflunomide0.000428%
BADD_D01475Mirabegron0.000161%
BADD_D01566Nifedipine--
BADD_D01831Prednisolone0.000087%
BADD_D01888Quetiapine0.000109%
BADD_D02016Sibutramine--
BADD_D02100Sunitinib0.000280%
BADD_D02165Teriflunomide0.000362%
BADD_D02334Vandetanib--
BADD_D02466Levomilnacipran0.000062%
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