Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Mallory-Weiss syndrome
ADR ID BADD_A02658
ADR Hierarchy
07      Gastrointestinal disorders
07.12      Gastrointestinal haemorrhages NEC
07.12.01      Gastric and oesophageal haemorrhages
07.12.01.004      Mallory-Weiss syndrome
24      Vascular disorders
24.07      Vascular haemorrhagic disorders
24.07.02      Gastrointestinal haemorrhages
24.07.02.038      Mallory-Weiss syndrome
Description A condition characterized by mucosal tears at the ESOPHAGOGASTRIC JUNCTION, sometimes with HEMATEMESIS. Typically it is caused by forceful bouts of retching or VOMITING. [MeSH]
MedDRA Code 10026712
MeSH ID D008309
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Gastro-oesophageal laceration-haemorrhage syndrome | Gastroesophageal laceration-hemorrhage syndrome | Mallory Weiss tear | Mallory-Weiss syndrome | Gastrooesophageal laceration-haemorrhage syndrome | Mallory-Weiss Syndrome | Mallory Weiss Syndrome | Syndrome, Mallory-Weiss | Mucosal Lacerations-Gastroesophageal Junction | Junction, Mucosal Lacerations-Gastroesophageal | Junctions, Mucosal Lacerations-Gastroesophageal | Lacerations-Gastroesophageal Junction, Mucosal | Lacerations-Gastroesophageal Junctions, Mucosal | Mucosal Lacerations Gastroesophageal Junction | Mucosal Lacerations-Gastroesophageal Junctions | Mallory-Weiss Tear | Mallory Weiss Tear | Gastroesophageal Laceration-Hemorrhage | Gastroesophageal Laceration Hemorrhage | Gastroesophageal Laceration-Hemorrhages | Laceration-Hemorrhage, Gastroesophageal | Laceration-Hemorrhages, Gastroesophageal | Mallory-Weiss Laceration | Laceration, Mallory-Weiss | Mallory Weiss Laceration
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000239%
BADD_D00504Clopidogrel0.000043%
BADD_D00563Dabigatran0.000979%
BADD_D00680Dimethyl fumarate0.000400%
BADD_D00686Diphenhydramine0.000134%
BADD_D01119Ibrutinib0.000112%
BADD_D01442Metoclopramide0.000196%
BADD_D01498Morphine0.000167%
BADD_D01633Oxaliplatin0.000224%
BADD_D01796Polyoxyethylene--
BADD_D01933Ribavirin0.005934%
BADD_D01954Rivaroxaban0.000728%
BADD_D02010Sertraline0.000064%
BADD_D02018Sildenafil0.000107%
BADD_D02100Sunitinib0.000112%
BADD_D02345Venetoclax0.000112%
BADD_D02373Warfarin0.000146%
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