Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Mania
ADR ID BADD_A02660
ADR Hierarchy
19      Psychiatric disorders
19.16      Manic and bipolar mood disorders and disturbances
19.16.02      Mood alterations with manic symptoms
19.16.02.002      Mania
Description A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. [CTCAE] A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. [MeSH]
MedDRA Code 10026749
MeSH ID D001714; D001714; D001714
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute mania | Atypical manic disorder | Change to manic state | Mania | Mania acute | Mania aggravated | Manic | Manic disorder, recurrent episode | Manic disorder, recurrent episode, in full remission | Manic disorder, recurrent episode, in partial or unspecified remission | Manic disorder, recurrent episode, mild degree | Manic disorder, recurrent episode, moderate degree | Manic disorder, recurrent episode, severe degree, specified as with psychotic behavior | Manic disorder, recurrent episode, severe degree, specified as with psychotic behaviour | Manic disorder, recurrent episode, severe degree, without mention psychotic behavior | Manic disorder, recurrent episode, severe degree, without mention psychotic behaviour | Manic disorder, recurrent episode, unspecified degree | Manic disorder, single episode | Manic disorder, single episode, in full remission | Manic disorder, single episode, in partial or unspecified remission | Manic disorder, single episode, mild degree | Manic disorder, single episode, moderate degree | Manic disorder, single episode, severe degree, specified as with psychotic behavior | Manic disorder, single episode, severe degree, specified as with psychotic behaviour | Manic disorder, single episode, severe degree, without mention of psychotic behavior | Manic disorder, single episode, unspecified degree | Manic episode | Manic excitement | Manic psychosis | Manic reaction | Manic state | Manic state aggravated | Oppression to conduct act | Psychosis manic | Reaction manic | Antibiomania | Bipolar Disorder | Bipolar Disorders | Disorder, Bipolar | Psychosis, Manic-Depressive | Psychosis, Manic Depressive | Manic-Depressive Psychosis | Manic Depressive Psychosis | Affective Psychosis, Bipolar | Bipolar Affective Psychosis | Psychoses, Bipolar Affective | Psychosis, Bipolar Affective | Psychoses, Manic-Depressive | Manic-Depressive Psychoses | Psychoses, Manic Depressive | Manias | Manic State | Manic States | State, Manic | States, Manic | Depression, Bipolar | Bipolar Depression | Manic Disorder | Disorder, Manic | Manic Disorders
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00924Fluocinolone acetonide--
BADD_D00932Fluoxetine0.000329%
BADD_D00933Fluoxetine hydrochloride--
BADD_D00950Fluvoxamine--
BADD_D00951Fluvoxamine maleate--
BADD_D00981Gabapentin--
BADD_D00996Galantamine0.001203%
BADD_D01003Ganciclovir--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01046Guanfacine0.000381%
BADD_D01086Hydrocortisone0.000138%
BADD_D01132Idursulfase--
BADD_D01133Ifosfamide--
BADD_D01134Iloperidone--
BADD_D01139Imipramine--
BADD_D01142Imiquimod0.000878%
BADD_D01167Interferon alfa-2b--
BADD_D01213Isotretinoin--
BADD_D01217Itraconazole0.002672%
BADD_D01220Ivacaftor-
BADD_D01228Ketamine0.000536%
BADD_D01243Lamotrigine0.000916%
BADD_D01257Letrozole0.000659%
BADD_D01265Levetiracetam0.001542%
BADD_D01275Levofloxacin0.000127%
BADD_D01280Levomilnacipran hydrochloride--
BADD_D01299Lisdexamfetamine dimesylate--
BADD_D01303Lithium carbonate0.002677%
BADD_D01304Lithium cation0.001767%
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