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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
Drug Name
Drug ID
ATC Code
DrugBank ID
KEGG ID
PubChem ID
CAS RN
Molecular Formula
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ADR Ontology
ADR Term
Middle insomnia
ADR ID
BADD_A02780
ADR Hierarchy
17
Nervous system disorders
17.15
Sleep disturbances (incl subtypes)
17.15.03
Disturbances in initiating and maintaining sleep
17.15.03.003
Middle insomnia
19
Psychiatric disorders
19.02
Sleep disorders and disturbances
19.02.01
Disturbances in initiating and maintaining sleep
19.02.01.003
Middle insomnia
Description
Not Available
MedDRA Code
10027590
MeSH ID
Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Arousal night | Middle insomnia | Nocturnal awakening | Sleep maintenance insomnia
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00837
Eszopiclone
0.000220%
BADD_D00891
Fesoterodine
0.001092%
BADD_D00898
Finasteride
0.000166%
BADD_D00946
Fluticasone furoate
-
-
BADD_D00947
Fluticasone propionate
-
-
BADD_D01046
Guanfacine
0.000467%
BADD_D01102
Hydroxybutanoic acid
-
-
BADD_D01258
Leucovorin
0.001239%
BADD_D01260
Leuprolide acetate
0.007314%
BADD_D01285
Levothyroxine
0.000038%
BADD_D01299
Lisdexamfetamine dimesylate
-
-
BADD_D01311
Lomitapide
0.000084%
BADD_D01317
Loratadine
0.000048%
BADD_D01330
Lurasidone
0.001672%
BADD_D01373
Melatonin
0.000511%
BADD_D01401
Metformin
0.000016%
BADD_D01418
Methotrexate
-
-
BADD_D01431
Methylphenidate
0.000041%
BADD_D01445
Metoprolol
0.000007%
BADD_D01476
Mirtazapine
0.000176%
BADD_D01496
Montelukast
0.000076%
BADD_D01533
Naproxen
-
-
BADD_D01567
Nilotinib
0.000302%
BADD_D01599
Olanzapine
0.000210%
BADD_D01630
Ospemifene
0.000396%
BADD_D01654
Palbociclib
0.003022%
BADD_D01656
Paliperidone
-
-
BADD_D01817
Pramipexole
-
-
BADD_D01818
Pramipexole dihydrochloride
-
-
BADD_D01831
Prednisolone
0.000077%
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