Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Mouth ulceration
ADR ID BADD_A02857
ADR Hierarchy
07      Gastrointestinal disorders
07.05      Oral soft tissue conditions
07.05.06      Stomatitis and ulceration
07.05.06.004      Mouth ulceration
Description A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842) [MeSH]
MedDRA Code 10028034
MeSH ID D019226; D005892
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Buccal mucosa ulceration | Buccal ulceration | Mouth ulcer | Mouth ulceration | Oral ulceration | Stomatitis ulcerative | Ulcer buccal | Ulcer mouth | Ulceration mouth | Ulceration of mouth | Ulcerative stomatitis | Ulcerative stomatitis, acute | Mouth ulceration aggravated | Mouth ulceration-aggravated | Perioral ulcer | Oral Ulcer | Oral Ulcers | Ulcer, Oral | Ulcers, Oral | Mouth Ulcer | Mouth Ulcers | Ulcer, Mouth | Ulcers, Mouth
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02241Tolcapone--
BADD_D02247Topiramate--
BADD_D02257Trametinib0.000817%
BADD_D02258Trametinib dimethyl sulfoxide--
BADD_D02270Tretinoin--
BADD_D02305Trospium--
BADD_D02319Urofollitropin--
BADD_D02320Urokinase--
BADD_D02323Valacyclovir--
BADD_D02324Valacyclovir hydrochloride--
BADD_D02326Valganciclovir--
BADD_D02329Valproic acid--
BADD_D02337Varenicline0.001187%
BADD_D02338Varenicline tartrate--
BADD_D02344Vemurafenib0.000336%
BADD_D02346Venlafaxine0.000064%
BADD_D02360Vincristine--
BADD_D02362Vinflunine--
BADD_D02365Vismodegib0.000627%
BADD_D02367Voltaren--
BADD_D02369Voriconazole0.015683%
BADD_D02379Zaleplon--
BADD_D02383Zidovudine--
BADD_D02396Zonisamide--
BADD_D02407Upadacitinib0.001640%
BADD_D02436Atorvastatin--
BADD_D02464Fingolimod0.002917%
BADD_D02473Sodium chloride0.000362%
BADD_D02483Ribociclib0.000548%
BADD_D02490Apalutamide0.000334%
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