Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Muscle spasms
ADR ID BADD_A02889
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.004      Muscle spasms
Description A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398) [MeSH]
MedDRA Code 10028334
MeSH ID D009120; D013035; D013746
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cramp | Cramp in hand | Cramp in legs thighs | Cramp legs | Cramp muscle | Cramp of limb | Cramps | Cramps calf | Cramps in legs | Cramps in the calves | Cramps leg | Cramps legs | Cramps of lower body | Cramps of lower extremities | Foot cramps | Generalized spasm | Leg cramps | Muscle cramp | Muscle cramps | Muscle cramps aggravated | Muscle spasm | Muscle spasms | Muscular spasm | Neck cramps | Night cramps | Nocturnal leg muscle cramps | Spasm generalised | Spasm generalized | Spasm muscle | Spasm of muscle | Spasms | Tetanic spasm generalized | Cervical spasm | Finger cramps | Systremma | Spasmophilia | Charley horse | Back muscle spasms | Generalised spasm | Tetanic spasm generalised | Cramps of upper extremities | Cramps of extremities | Toe cramps | Leg spasm | Muscle Cramp | Cramp, Muscle | Cramps, Muscle | Muscle Cramps | Muscular Cramp | Cramp, Muscular | Cramps, Muscular | Muscular Cramps | Limb Cramp | Cramp, Limb | Cramps, Limb | Limb Cramps
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01392Mercaptopurine--
BADD_D01395Mersyndol--
BADD_D01397Mesalamine--
BADD_D01401Metformin--
BADD_D01405Methadone--
BADD_D01415Methocarbamol0.000343%
BADD_D01420Methoxsalen--
BADD_D01421Methoxy polyethylene glycol-epoetin beta--
BADD_D01423Methyclothiazide--
BADD_D01428Methylergonovine--
BADD_D01429Methylergonovine maleate--
BADD_D01430Methylnaltrexone bromide--
BADD_D01431Methylphenidate--
BADD_D01439Methysergide--
BADD_D01442Metoclopramide--
BADD_D01444Metolazone--
BADD_D01445Metoprolol--
BADD_D01449Metronidazole--
BADD_D01452Mexiletine--
BADD_D01457Miconazole--
BADD_D01458Miconazole nitrate--
BADD_D01461Midodrine--
BADD_D01462Midodrine hydrochloride--
BADD_D01463Mifepristone0.001312%
BADD_D01465Miglustat--
BADD_D01476Mirtazapine--
BADD_D01477Misoprostol0.002589%
BADD_D01482Mivacurium chloride--
BADD_D01484Modafinil0.000617%
BADD_D01487Molindone--
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