Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Myeloid metaplasia
ADR ID BADD_A02930
ADR Hierarchy
01      Blood and lymphatic system disorders
01.13      Haematopoietic neoplasms (excl leukaemias and lymphomas)
01.13.03      Myeloproliferative disorders (excl leukaemias)
01.13.03.004      Myeloid metaplasia
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.21      Haematopoietic neoplasms (excl leukaemias and lymphomas)
16.21.03      Myeloproliferative disorders (excl leukaemias)
16.21.03.005      Myeloid metaplasia
Description A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone. [MeSH]
MedDRA Code 10028561
MeSH ID D055728
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Metaplasia myeloid | Myeloid metaplasia | Primary Myelofibrosis | Myelofibroses, Primary | Myelofibrosis, Primary | Primary Myelofibroses | Bone Marrow Fibrosis | Bone Marrow Fibroses | Fibroses, Bone Marrow | Fibrosis, Bone Marrow | Myelofibrosis | Myelofibroses | Idiopathic Myelofibrosis | Myeloid Metaplasia | Metaplasia, Myeloid | Metaplasias, Myeloid | Myeloid Metaplasias | Myelosclerosis | Myeloscleroses | Myelosis, Nonleukemic | Myeloses, Nonleukemic | Nonleukemic Myeloses | Nonleukemic Myelosis | Chronic Idiopathic Myelofibrosis | Agnogenic Myeloid Metaplasia | Agnogenic Myeloid Metaplasias | Metaplasia, Agnogenic Myeloid | Metaplasias, Agnogenic Myeloid | Myeloid Metaplasia, Agnogenic | Myeloid Metaplasias, Agnogenic | Myelofibrosis With Myeloid Metaplasia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01452Mexiletine--
BADD_D01835Pregabalin--
BADD_D02007Semaxanib--
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