Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Myoclonus
ADR ID BADD_A02940
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.008      Myoclonus
Description Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may be a feature of some CENTRAL NERVOUS SYSTEM DISEASES; (e.g., EPILEPSY, MYOCLONIC). Nocturnal myoclonus is the principal feature of the NOCTURNAL MYOCLONUS SYNDROME. (From Adams et al., Principles of Neurology, 6th ed, pp102-3). [MeSH]
MedDRA Code 10028622
MeSH ID D009207
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Myclonic jerks | Myoclonic jerks | Myoclonus | Palatal myoclonus | Negative myoclonus | Positive myoclonus | Hypnagogic myoclonus | Hypnic jerk | Myoclonic Jerking | Jerking, Myoclonic | Myoclonic Jerk | Jerk, Myoclonic | Jerks, Myoclonic | Myoclonic Jerks | Myoclonus Simplex | Simplex, Myoclonus | Myoclonus, Action | Action Myoclonus | Myoclonus, Eyelid | Eyelid Myoclonus | Myoclonus, Intention | Intention Myoclonus | Myoclonus, Upper Extremity | Extremity Myoclonus, Upper | Upper Extremity Myoclonus | Polymyoclonus | Myoclonus, Nocturnal | Nocturnal Myoclonus | Myoclonus, Sleep | Sleep Myoclonus | Myoclonus, Oculopalatal | Oculopalatal Myoclonus | Myoclonus, Palatal | Palatal Myoclonus | Myoclonus, Segmental | Segmental Myoclonus | Myoclonus, Lower Extremity | Extremity Myoclonus, Lower | Lower Extremity Myoclonus
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01317Loratadine0.000032%
BADD_D01318Lorazepam0.000145%
BADD_D01350Maprotiline--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01378Memantine0.001112%
BADD_D01379Memantine hydrochloride--
BADD_D01384Meperidine--
BADD_D01385Meperidine hydrochloride--
BADD_D01393Meropenem0.000049%
BADD_D01405Methadone0.001061%
BADD_D01442Metoclopramide0.001608%
BADD_D01449Metronidazole0.000105%
BADD_D01476Mirtazapine0.000120%
BADD_D01498Morphine0.003486%
BADD_D01506Muromonab-cd3--
BADD_D01522Nalmefene--
BADD_D01523Nalmefene hydrochloride--
BADD_D01546Nefazodone--
BADD_D01547Nefazodone hydrochloride--
BADD_D01587Norfloxacin--
BADD_D01599Olanzapine0.001831%
BADD_D01633Oxaliplatin--
BADD_D01637Oxcarbazepine0.000596%
BADD_D01656Paliperidone--
BADD_D01676Paricalcitol--
BADD_D01679Paroxetine0.000116%
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
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