Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Myoclonus
ADR ID BADD_A02940
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.008      Myoclonus
Description Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may be a feature of some CENTRAL NERVOUS SYSTEM DISEASES; (e.g., EPILEPSY, MYOCLONIC). Nocturnal myoclonus is the principal feature of the NOCTURNAL MYOCLONUS SYNDROME. (From Adams et al., Principles of Neurology, 6th ed, pp102-3). [MeSH]
MedDRA Code 10028622
MeSH ID D009207
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Myclonic jerks | Myoclonic jerks | Myoclonus | Palatal myoclonus | Negative myoclonus | Positive myoclonus | Hypnagogic myoclonus | Hypnic jerk | Myoclonic Jerking | Jerking, Myoclonic | Myoclonic Jerk | Jerk, Myoclonic | Jerks, Myoclonic | Myoclonic Jerks | Myoclonus Simplex | Simplex, Myoclonus | Myoclonus, Action | Action Myoclonus | Myoclonus, Eyelid | Eyelid Myoclonus | Myoclonus, Intention | Intention Myoclonus | Myoclonus, Upper Extremity | Extremity Myoclonus, Upper | Upper Extremity Myoclonus | Polymyoclonus | Myoclonus, Nocturnal | Nocturnal Myoclonus | Myoclonus, Sleep | Sleep Myoclonus | Myoclonus, Oculopalatal | Oculopalatal Myoclonus | Myoclonus, Palatal | Palatal Myoclonus | Myoclonus, Segmental | Segmental Myoclonus | Myoclonus, Lower Extremity | Extremity Myoclonus, Lower | Lower Extremity Myoclonus
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02099Sumatriptan succinate--
BADD_D02105Tacrolimus--
BADD_D02210Tiagabine--
BADD_D02211Tiagabine hydrochloride--
BADD_D02241Tolcapone--
BADD_D02247Topiramate0.000126%
BADD_D02254Tramadol0.000082%
BADD_D02259Trandolapril--
BADD_D02261Tranexamic acid0.052997%
BADD_D02262Tranylcypromine--
BADD_D02263Tranylcypromine sulfate--
BADD_D02326Valganciclovir--
BADD_D02329Valproic acid0.000699%
BADD_D02346Venlafaxine0.000119%
BADD_D02347Venlafaxine hydrochloride--
BADD_D02355Vigabatrin0.000336%
BADD_D02360Vincristine--
BADD_D02369Voriconazole0.008713%
BADD_D02379Zaleplon--
BADD_D02389Ziprasidone hydrochloride--
BADD_D02391Ziprasidone mesylate--
BADD_D02394Zolpidem0.000064%
BADD_D02396Zonisamide0.000912%
BADD_D02412Octreotide--
BADD_D02439Levodopa0.000367%
BADD_D02473Sodium chloride0.000241%
BADD_D02577Oseltamivir acid0.000248%
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