Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Narcolepsy
ADR ID BADD_A02958
ADR Hierarchy
17      Nervous system disorders
17.15      Sleep disturbances (incl subtypes)
17.15.01      Narcolepsy and hypersomnia
17.15.01.002      Narcolepsy
19      Psychiatric disorders
19.02      Sleep disorders and disturbances
19.02.02      Narcolepsy and associated conditions
19.02.02.002      Narcolepsy
Description A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7) [MeSH]
MedDRA Code 10028713
MeSH ID D009290
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cataplexy and narcolepsy | Idiopathic narcolepsy | Narcolepsy | Narcolepsy with cataplexy | Narcolepsy aggravated | Paroxysmal Sleep | Sleep, Paroxysmal | Narcoleptic Syndrome | Narcoleptic Syndromes | Syndrome, Narcoleptic | Syndromes, Narcoleptic | Gelineau Syndrome | Syndrome, Gelineau | Gelineau's Syndrome | Gelineau's Syndromes | Gelineaus Syndrome | Syndrome, Gelineau's | Syndromes, Gelineau's | Narcolepsy-Cataplexy Syndrome | Narcolepsy Cataplexy Syndrome | Narcolepsy-Cataplexy Syndromes | Syndrome, Narcolepsy-Cataplexy | Syndromes, Narcolepsy-Cataplexy
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00165Aripiprazole0.000079%
BADD_D00310Buprenorphine0.001412%
BADD_D00475Citalopram0.000067%
BADD_D00621Desvenlafaxine0.000178%
BADD_D00680Dimethyl fumarate0.000880%
BADD_D00932Fluoxetine0.000030%
BADD_D00981Gabapentin0.000026%
BADD_D01431Methylphenidate0.000082%
BADD_D01484Modafinil0.000823%
BADD_D01817Pramipexole0.000159%
BADD_D01818Pramipexole dihydrochloride--
BADD_D01827Prazosin--
BADD_D01835Pregabalin0.000182%
BADD_D02047Sodium oxybate0.002575%
BADD_D02346Venlafaxine0.000032%
BADD_D02464Fingolimod0.001013%
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