Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Nephrotic syndrome
ADR ID BADD_A03027
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.002      Nephrotic syndrome
Description A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. [CTCAE] Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. [MeSH]
MedDRA Code 10029164
MeSH ID D009401; D009404
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Nephrosis | Nephrosis osmotic | Nephrotic syndrome | Nephrotic syndrome in diseases classified elsewhere | Nephrotic syndrome with lesion of membranoproliferative glomerulonephritis | Nephrotic syndrome with lesion of membranous glomerulonephritis | Nephrotic syndrome with lesion of minimal change glomerulonephritis | Nephrotic syndrome with lesion of proliferative glomerulonephritis | Nephrotic syndrome with other pathological lesion in kidney | Nephrotic syndrome with other specified pathological lesion in kidney | Nephrotic syndrome with unspecified pathological lesion in kidney | Syndrome nephrotic | Nephrotic syndrome worsened | Steroid-resistant nephrotic syndrome | Nephroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.000501%
BADD_D00029Acetyl sulfisoxazole--
BADD_D00039Acyclovir0.000071%
BADD_D00049Agalsidase beta--
BADD_D00066Alendronic acid0.000044%
BADD_D00071Alglucosidase alfa--
BADD_D00121Amlodipine0.000016%
BADD_D00132Amphotericin b--
BADD_D00191Auranofin--
BADD_D00193Axitinib0.001399%
BADD_D00195Azathioprine0.000470%
BADD_D00203Azithromycin0.000006%
BADD_D00221Bedaquiline0.001027%
BADD_D00271Bicalutamide0.001406%
BADD_D00318Busulfan--
BADD_D00330Cabozantinib0.001388%
BADD_D00354Captopril--
BADD_D00356Carbamazepine0.000186%
BADD_D00367Carfilzomib0.000224%
BADD_D00410Celecoxib--
BADD_D00416Certolizumab pegol--
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00429Chlorambucil--
BADD_D00463Cidofovir--
BADD_D00480Clarithromycin0.000223%
BADD_D00504Clopidogrel0.000064%
BADD_D00508Clostridium tetani toxoid immune globulin (human)--
BADD_D00537Cromoglycate--
BADD_D00551Cyclosporine0.001160%
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