Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Nephrotic syndrome
ADR ID BADD_A03027
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.002      Nephrotic syndrome
Description A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. [CTCAE] Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. [MeSH]
MedDRA Code 10029164
MeSH ID D009401; D009404
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Nephrosis | Nephrosis osmotic | Nephrotic syndrome | Nephrotic syndrome in diseases classified elsewhere | Nephrotic syndrome with lesion of membranoproliferative glomerulonephritis | Nephrotic syndrome with lesion of membranous glomerulonephritis | Nephrotic syndrome with lesion of minimal change glomerulonephritis | Nephrotic syndrome with lesion of proliferative glomerulonephritis | Nephrotic syndrome with other pathological lesion in kidney | Nephrotic syndrome with other specified pathological lesion in kidney | Nephrotic syndrome with unspecified pathological lesion in kidney | Syndrome nephrotic | Nephrotic syndrome worsened | Steroid-resistant nephrotic syndrome | Nephroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01145Immunoglobulin g (human)--
BADD_D01156Indomethacin--
BADD_D01167Interferon alfa-2b--
BADD_D01181Iopamidol--
BADD_D01204Isoniazid0.006949%
BADD_D01231Ketoprofen--
BADD_D01233Ketorolac tromethamine--
BADD_D01242Lamivudine0.001012%
BADD_D01254Lenvatinib0.002250%
BADD_D01257Letrozole0.000395%
BADD_D01258Leucovorin0.001859%
BADD_D01275Levofloxacin0.000190%
BADD_D01295Linezolid0.003293%
BADD_D01349Mannitol--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01368Mefenamic acid--
BADD_D01374Meloxicam0.000040%
BADD_D01386Mephenytoin--
BADD_D01397Mesalamine0.000457%
BADD_D01431Methylphenidate0.000082%
BADD_D01433Methylprednisolone0.000048%
BADD_D01449Metronidazole0.000053%
BADD_D01496Montelukast0.000044%
BADD_D01507Mycophenolate mofetil--
BADD_D01508Mycophenolic acid0.001427%
BADD_D01511Nabumetone0.000260%
BADD_D01533Naproxen--
BADD_D01534Naproxen sodium--
BADD_D01567Nilotinib0.000616%
BADD_D01607Olsalazine--
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