Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Neuropathic arthropathy
ADR ID BADD_A03062
ADR Hierarchy
17      Nervous system disorders
17.09      Peripheral neuropathies
17.09.03      Peripheral neuropathies NEC
17.09.03.008      Neuropathic arthropathy
05      Endocrine disorders
05.07      Diabetic complications
05.07.04      Diabetic complications neurological
05.07.04.011      Neuropathic arthropathy
14      Metabolism and nutrition disorders
14.07      Diabetic complications
14.07.04      Diabetic complications neurological
14.07.04.011      Neuropathic arthropathy
15      Musculoskeletal and connective tissue disorders
15.01      Joint disorders
15.01.04      Osteoarthropathies
15.01.04.008      Neuropathic arthropathy
Description Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. It is probably a complication of a variety of neurologic disorders, particularly TABES DORSALIS, involving loss of sensation, which leads to relaxation of supporting structures and chronic instability of the joint. (Dorland, 27th ed) [MeSH]
MedDRA Code 10029326
MeSH ID D001177
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Arthritis Charcot-type | Arthropathy associated with neurological disorders | Arthropathy neurogenic | Charcot arthropathy | Charcot's joint | Charcot's syndrome | Diabetic arthropathy | Neuropathic arthropathy | Charcot fracture | Diabetic osteoarthropathy | Charcot foot | Arthropathy, Neurogenic | Arthropathies, Neurogenic | Neurogenic Arthropathies | Neurogenic Arthropathy | Charcot's Joint | Charcot Joint | Charcots Joint | Joint, Charcot's
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00344Canagliflozin0.000630%
BADD_D01091Hydrocortisone sodium succinate--
BADD_D01258Leucovorin0.001239%
BADD_D01401Metformin0.000008%
BADD_D01433Methylprednisolone--
BADD_D01434Methylprednisolone acetate--
BADD_D01435Methylprednisolone hemisuccinate--
BADD_D01436Methylprednisolone sodium succinate--
BADD_D01798Pomalidomide0.000651%
BADD_D01832Prednisolone acetate--
BADD_D01835Pregabalin0.000052%
BADD_D02105Tacrolimus0.000297%
BADD_D02272Triamcinolone acetonide--
BADD_D02273Triamcinolone diacetate--
BADD_D02274Triamcinolone hexacetonide--
BADD_D02436Atorvastatin0.000005%
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