Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Osteochondrosis
ADR ID BADD_A03215
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.07      Tendon, ligament and cartilage disorders
15.07.03      Cartilage disorders
15.07.03.002      Osteochondrosis
Description Any of a group of bone disorders involving one or more ossification centers (EPIPHYSES). It is characterized by degeneration or NECROSIS followed by revascularization and reossification. Osteochondrosis often occurs in children causing varying degrees of discomfort or pain. There are many eponymic types for specific affected areas, such as tarsal navicular (Kohler disease) and tibial tuberosity (Osgood-Schlatter disease). [MeSH]
MedDRA Code 10031233
MeSH ID D055034; D012544; D010008; D055035; D010020
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Adult osteochondrosis of spine | Epiphyseal ischaemic necrosis | Epiphyseal ischemic necrosis | Juvenile osteochondrosis | Juvenile osteochondrosis of foot | Juvenile osteochondrosis of lower extremity, excluding foot | Juvenile osteochondrosis of spine | Juvenile osteochondrosis of upper extremity | Osgood-Schlatter's disease | Osteochondritis dissecans | Osteochondrosis | Osteochondrosis juvenilis | Osteochondrosis of foot | Osteochondrosis of leg (excl hip) | Osteochondrosis of tibial tubercle | Osteochondrosis of upper limb | Other juvenile osteochondrosis | Scheuermann's disease | Schuermann's disease | Freiberg's disease | Sinding-Larsen-Johansson disease | Osteochondrosis of spine | Kienbock's disease | Vertebral osteochondrosis | Osteochondral defects | Osteochondritis of spine | Panner disease | Osteochondroses | Osgood-Schlatter Disease | Osgood Schlatter Disease | Koehler Disease | Navicular Osteochondrosis | Navicular Osteochondroses | Osteochondroses, Navicular | Osteochondrosis, Navicular | Koehler's Disease | Koehlers Disease
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D00504Clopidogrel0.000021%
BADD_D00602Delamanid--
BADD_D00653Diclofenac0.000026%
BADD_D00861Exemestane--
BADD_D00898Finasteride0.000045%
BADD_D01243Lamotrigine0.000083%
BADD_D01265Levetiracetam0.000437%
BADD_D01285Levothyroxine0.000005%
BADD_D01831Prednisolone0.000087%
BADD_D02031Sitaxentan--
BADD_D02222Tinzaparin sodium--
BADD_D02329Valproic acid0.000100%
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