Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Osteolysis
ADR ID BADD_A03218
ADR Hierarchy
14      Metabolism and nutrition disorders
14.04      Bone, calcium, magnesium and phosphorus metabolism disorders
14.04.04      Bone metabolism disorders
14.04.04.006      Osteolysis
15      Musculoskeletal and connective tissue disorders
15.02      Bone disorders (excl congenital and fractures)
15.02.03      Metabolic bone disorders
15.02.03.008      Osteolysis
Description Dissolution of bone that particularly involves the removal or loss of calcium. [MeSH]
MedDRA Code 10031248
MeSH ID D010014; D030981
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acroosteolysis | Osteolysis | Osteolytic lesion | Osteolyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000176%
BADD_D00142Anastrozole0.000238%
BADD_D00284Bortezomib0.000224%
BADD_D00623Dexamethasone0.000145%
BADD_D00849Etidronic acid--
BADD_D00858Everolimus0.000306%
BADD_D00978Fulvestrant0.000334%
BADD_D01119Ibrutinib0.000112%
BADD_D01253Lenalidomide0.004002%
BADD_D01455Micafungin0.000150%
BADD_D01498Morphine0.000111%
BADD_D01567Nilotinib0.000112%
BADD_D01798Pomalidomide0.001254%
BADD_D01831Prednisolone0.000035%
BADD_D02058Sorafenib0.000224%
BADD_D02154Tenofovir0.001939%
BADD_D02373Warfarin0.000028%
BADD_D02392Zoledronic acid0.011452%
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