Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Osteomalacia
ADR ID BADD_A03219
ADR Hierarchy
14      Metabolism and nutrition disorders
14.04      Bone, calcium, magnesium and phosphorus metabolism disorders
14.04.04      Bone metabolism disorders
14.04.04.001      Osteomalacia
15      Musculoskeletal and connective tissue disorders
15.02      Bone disorders (excl congenital and fractures)
15.02.03      Metabolic bone disorders
15.02.03.001      Osteomalacia
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.01      Renal failure complications
20.01.01.002      Osteomalacia
Description Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis. [MeSH]
MedDRA Code 10031250
MeSH ID D010018
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Adult rickets | Osteomalacia | Osteomalacia, unspecified | Adult Rickets | Rickets, Adult
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00025Acetazolamide--
BADD_D00043Adefovir--
BADD_D00044Adefovir dipivoxil0.035282%
BADD_D00066Alendronic acid0.000132%
BADD_D00356Carbamazepine0.000279%
BADD_D00673Dihydrogen phosphate--
BADD_D00749Efavirenz--
BADD_D00766Emtricitabine--
BADD_D00848Etidronate disodium--
BADD_D00849Etidronic acid--
BADD_D00981Gabapentin0.000016%
BADD_D01021Glatiramer acetate--
BADD_D01133Ifosfamide--
BADD_D01197Iron--
BADD_D01242Lamivudine0.003542%
BADD_D01752Phenobarbital--
BADD_D01765Phenytoin0.000478%
BADD_D01766Phenytoin sodium--
BADD_D02154Tenofovir0.011632%
BADD_D02155Tenofovir disoproxil--
BADD_D02156Tenofovir disoproxil fumarate--
BADD_D02247Topiramate--
BADD_D02369Voriconazole--
BADD_D02392Zoledronic acid0.011452%
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