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ADReCS ID
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ADR Ontology
ADR Term
Osteomalacia
ADR ID
BADD_A03219
ADR Hierarchy
14
Metabolism and nutrition disorders
14.04
Bone, calcium, magnesium and phosphorus metabolism disorders
14.04.04
Bone metabolism disorders
14.04.04.001
Osteomalacia
15
Musculoskeletal and connective tissue disorders
15.02
Bone disorders (excl congenital and fractures)
15.02.03
Metabolic bone disorders
15.02.03.001
Osteomalacia
20
Renal and urinary disorders
20.01
Renal disorders (excl nephropathies)
20.01.01
Renal failure complications
20.01.01.002
Osteomalacia
Description
Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis. [MeSH]
MedDRA Code
10031250
MeSH ID
D010018
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Adult rickets | Osteomalacia | Osteomalacia, unspecified | Adult Rickets | Rickets, Adult
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00025
Acetazolamide
-
-
BADD_D00043
Adefovir
-
-
BADD_D00044
Adefovir dipivoxil
0.035282%
BADD_D00066
Alendronic acid
0.000132%
BADD_D00356
Carbamazepine
0.000279%
BADD_D00673
Dihydrogen phosphate
-
-
BADD_D00749
Efavirenz
-
-
BADD_D00766
Emtricitabine
-
-
BADD_D00848
Etidronate disodium
-
-
BADD_D00849
Etidronic acid
-
-
BADD_D00981
Gabapentin
0.000016%
BADD_D01021
Glatiramer acetate
-
-
BADD_D01133
Ifosfamide
-
-
BADD_D01197
Iron
-
-
BADD_D01242
Lamivudine
0.003542%
BADD_D01752
Phenobarbital
-
-
BADD_D01765
Phenytoin
0.000478%
BADD_D01766
Phenytoin sodium
-
-
BADD_D02154
Tenofovir
0.011632%
BADD_D02155
Tenofovir disoproxil
-
-
BADD_D02156
Tenofovir disoproxil fumarate
-
-
BADD_D02247
Topiramate
-
-
BADD_D02369
Voriconazole
-
-
BADD_D02392
Zoledronic acid
0.011452%
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