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ADR Ontology
ADR Term
Osteoporotic fracture
ADR ID
BADD_A03223
ADR Hierarchy
12
Injury, poisoning and procedural complications
12.04
Bone and joint injuries
12.04.02
Fractures and dislocations NEC
12.04.02.005
Osteoporotic fracture
14
Metabolism and nutrition disorders
14.04
Bone, calcium, magnesium and phosphorus metabolism disorders
14.04.04
Bone metabolism disorders
14.04.04.007
Osteoporotic fracture
15
Musculoskeletal and connective tissue disorders
15.08
Fractures
15.08.02
Fractures NEC
15.08.02.007
Osteoporotic fracture
Description
Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS. [MeSH]
MedDRA Code
10031290
MeSH ID
D058866
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Fracture due to osteoporosis | Osteoporosis fracture | Osteoporosis with fracture | Osteoporotic fracture | Osteoporotic Fractures | Fracture, Osteoporotic | Fractures, Osteoporotic | Osteoporotic Fracture
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00066
Alendronic acid
0.000176%
BADD_D00142
Anastrozole
-
-
BADD_D00271
Bicalutamide
-
-
BADD_D00335
Calcitonin
-
-
BADD_D00861
Exemestane
-
-
BADD_D00898
Finasteride
0.000045%
BADD_D01217
Itraconazole
0.002672%
BADD_D01257
Letrozole
0.000659%
BADD_D01365
Medroxyprogesterone
-
-
BADD_D01366
Medroxyprogesterone acetate
-
-
BADD_D01433
Methylprednisolone
0.000048%
BADD_D01476
Mirtazapine
-
-
BADD_D01831
Prednisolone
0.000280%
BADD_D01834
Prednisone
0.000058%
BADD_D01950
Risedronic acid
-
-
BADD_D02154
Tenofovir
0.006786%
BADD_D02375
Water
-
-
BADD_D02392
Zoledronic acid
0.004294%
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